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Simpler Grants

No. RFA-CA-27-005 · National Institutes of Health

Open

Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)

grants.gov listing
Dealbreakers No cost share required Audit: not stated Reimbursement-only: not stated
Award range
Not specified
Expected awards
Not specified
Application deadline
Oct 1, 2026 29 days left
Posted
Aug 31, 2026
Last verified
4 days ago

At a glance

No plain-language summary yet for this grant — the official description below is the best source.

What it funds

  • Health
  • Research & Discovery
  • Patients & People with Health Conditions
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on novel therapies for adult glioblastoma (GBM). The goal is to improve the treatment of adult GBM by developing novel effective agents that can cross the blood brain barrier (BBB) and testing them clinically. Successful early-stage trials of new drugs from this NOFO would transition seamlessly to later stage trials using well-established NCI clinical trial mechanisms. To implement this concept, a highly collaborative GBM Therapeutics Network (GTN) of cross-cutting teams will be established, each team capable of driving therapeutic agent(s) from pre-clinical development, through IND studies, into pilot clinical studies in humans. Appropriate therapeutic agents include: (1) novel agents or (2) agents or combinations approved for other indications and repurposed for treatment of GBM following appropriate preclinical studies. The scope of the NOFO, from late pre-clinical through early (Phase 0/1) clinical studies, uniquely spans a gap in the GBM drug development process.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide
Set-aside Set aside or prioritized for: Faith-based organization
“Faith-based or Community-based Organizations” — From the announcement

Program history

USASpending.gov

Assistance listing 93.394 · Cancer Detection and Diagnosis Research

Real awards this federal program has made — the whole assistance listing (93.394), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 137 $595,012 $414,585 – $662,610
FY 2025 184 $726,875 $399,923 – $1,297,708
FY 2024 215 $1,129,641 $414,953 – $1,862,878
FY 2023 268 $1,754,736 $438,924 – $2,398,100
FY 2022 277 $2,036,627 $596,368 – $3,077,027
FY 2021 269 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 1,350 — award counts are complete.

Who wins it Higher education (836), Nonprofit (284), Business (196) of 1,350 awards — categories can overlap.
Top states CA (184) · NY (79) · MA (78) · TX (66) · PA (26)
Largest recent awards
  1. TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $8,347,015 · FY 2022
  2. BATTELLE MEMORIAL INSTITUTE $6,630,183 · FY 2022
  3. THE JOHNS HOPKINS UNIVERSITY $6,618,085 · FY 2022
  4. SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH $6,181,895 · FY 2022
  5. OREGON HEALTH & SCIENCE UNIVERSITY $5,771,926 · FY 2022

Source: USASpending.gov · refreshed Aug 14, 2026

Assistance listing 93.395 · Cancer Treatment Research

Real awards this federal program has made — the whole assistance listing (93.395), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 316 $565,152 $413,691 – $664,926
FY 2025 435 $677,787 $402,400 – $1,233,798
FY 2024 488 $1,140,586 $408,966 – $1,897,871
FY 2023 522 — —
FY 2022 519 — —
FY 2021 517 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 2,797 — award counts are complete.

Who wins it Higher education (1,714), Nonprofit (603), Business (391) of 2,797 awards — categories can overlap.
Top states CA (132) · NY (107) · TX (87) · MA (66) · PA (59)
Largest recent awards
  1. THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER $6,902,371 · FY 2024
  2. VIRGINIA COMMONWEALTH UNIVERSITY $5,325,147 · FY 2024
  3. MASSACHUSETTS INSTITUTE OF TECHNOLOGY $4,597,865 · FY 2024
  4. PRIVO TECHNOLOGIES, INC. $4,499,992 · FY 2024
  5. FRED HUTCHINSON CANCER CENTER $4,234,248 · FY 2025

Source: USASpending.gov · refreshed Aug 18, 2026

Change history

Since we first indexed it
  1. Sep 1, 2026 Title updated
  2. Sep 1, 2026 Status: forecasted → open
  3. Sep 1, 2026 Deadline set: Oct 1, 2026