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Simpler Grants

No. PAR-27-127 · National Institutes of Health

Open

Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)

grants.gov listing
Dealbreakers No cost share required Audit: not stated Reimbursement-only: not stated
Award range
Up to $2,000,000
Expected awards
Not specified
Application deadline
May 25, 2028
Posted
Sep 1, 2026
Last verified
2 days ago

At a glance

No plain-language summary yet for this grant — the official description below is the best source.

What it funds

  • Health
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
  • Mental & Behavioral Health
Official description from grants.gov

The National Institute of Mental Health (NIMH) seeks research applications for the Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. Primary research objectives include 1) advancing the state of science in basic brain and behavior research to uncover and dissect the underlying mechanisms that will ultimately provide the foundation for understanding mental disorders, 2) supporting the integration and translation of basic and clinical neuroscience research on severe mental illnesses, and/or 3) advancing our understanding of the neurobehavioral developmental mechanisms and trajectories of psychopathology that begin in childhood and adolescence. Research teams that work at different levels of analysis and employ integrative, novel, and creative experimental approaches to address high-risk, high-impact questions are encouraged. Applications are not being solicited at this time. This Notice is being issued to provide potential applicants ample time to develop strong, collaborative, and responsive project plans. Research teams with expertise and insights in basic neuroscience or translational research that demonstrate an extraordinary level of synergy, integration, and potential for advancing the state of the field are encouraged to consider applying to the NOFO.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.242 · Mental Health Research Grants

Real awards this federal program has made — the whole assistance listing (93.242), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 491 $451,000 $167,702 – $811,948
FY 2025 600 $731,738 $320,544 – $1,460,736
FY 2024 883 — —
FY 2023 898 — —
FY 2022 986 — —
FY 2021 945 — —

For comparison, this notice advertises Up to $2,000,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 4,803 — award counts are complete.

Who wins it Higher education (3,532), Nonprofit (816), Business (215) of 4,803 awards — categories can overlap.
Top states CA (166) · NY (127) · MA (104) · PA (79) · IL (22)
Largest recent awards
  1. MASSACHUSETTS INSTITUTE OF TECHNOLOGY $21,714,815 · FY 2025
  2. OHIO STATE UNIVERSITY, THE $19,515,757 · FY 2025
  3. ALBERT EINSTEIN COLLEGE OF MEDICINE $18,270,924 · FY 2025
  4. DUKE UNIVERSITY $15,039,330 · FY 2025
  5. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $12,007,972 · FY 2026

Source: USASpending.gov · refreshed Aug 6, 2026

Change history

Since we first indexed it
  1. Sep 2, 2026 Status: forecasted → open
  2. Sep 2, 2026 Deadline set: May 25, 2028
  3. Sep 1, 2026 Title updated