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Simpler Grants

No. PA-24-190 · National Institutes of Health

Open

Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)

grants.gov listing Full announcement (NOFO)
Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement
Award range
Not specified
Expected awards
Not specified
Application deadline
May 7, 2027
Posted
Apr 23, 2024
Last verified
6 days ago

At a glance

AI summary

This NIH K25 program supports mentored career development for quantitative scientists and engineers who want to move into biomedical, behavioral, bioimaging, or bioengineering research, and this notice is only for applicants proposing an independent clinical trial, a feasibility study, or a separate ancillary clinical trial. Eligible applicants include a wide range of U.S. organizations, including nonprofits, universities, governments, small businesses, and foreign organizations, but non-U.S. entities are not eligible to apply and applications with foreign subawards or subcontracts are not allowed. The award period may not exceed 5 years, and participating NIH institutes provide salary, fringe benefits, and research development costs for items such as tuition, supplies, equipment, technical personnel, travel, and statistical services. No cost sharing is required, and indirect costs are reimbursed at 8% of modified total direct costs.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Environment
  • Food and Nutrition
  • Health
  • Income Security and Social Services
  • Training, Fellowship & Career Development
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.113 · Environmental Health

Real awards this federal program has made — the whole assistance listing (93.113), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 149 $379,262 $119,524 – $644,459
FY 2025 210 $431,750 $254,376 – $1,187,118
FY 2024 281 $583,878 $300,000 – $1,672,899
FY 2023 242 $587,197 $216,320 – $1,842,227
FY 2022 258 $465,538 $259,613 – $2,117,638
FY 2021 239 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 1,379 — award counts are complete.

Who wins it Higher education (1,027), Nonprofit (157), Business (146) of 1,379 awards — categories can overlap.
Top states CA (132) · NY (120) · MA (87) · NC (66) · TX (40)
Largest recent awards
  1. VANDERBILT UNIVERSITY MEDICAL CENTER $32,769,976 · FY 2023
  2. NORTH CAROLINA STATE UNIVERSITY $10,038,112 · FY 2023
  3. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $9,460,610 · FY 2022
  4. THE JOHNS HOPKINS UNIVERSITY $9,120,320 · FY 2022
  5. TRUSTEES OF BOSTON UNIVERSITY $8,944,898 · FY 2023

Source: USASpending.gov · refreshed Aug 16, 2026

Assistance listing 93.173 · Research Related to Deafness and Communication Disorders

Real awards this federal program has made — the whole assistance listing (93.173), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 170 $416,419 $134,042 – $648,731
FY 2025 238 $418,797 $187,647 – $1,008,401
FY 2024 283 $464,268 $152,978 – $1,268,772
FY 2023 260 $689,002 $272,758 – $1,868,608
FY 2022 286 $570,000 $145,264 – $2,113,099
FY 2021 246 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 1,483 — award counts are complete.

Who wins it Higher education (1,127), Nonprofit (192), Business (83) of 1,483 awards — categories can overlap.
Top states MA (107) · CA (101) · NY (89) · PA (78) · MD (30)
Largest recent awards
  1. REGENTS OF THE UNIVERSITY OF MINNESOTA $4,621,171 · FY 2022
  2. UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES $4,589,310 · FY 2023
  3. THE JOHNS HOPKINS UNIVERSITY $4,474,844 · FY 2022
  4. OREGON HEALTH & SCIENCE UNIVERSITY $3,863,432 · FY 2022
  5. THE LELAND STANFORD JUNIOR UNIVERSITY $3,579,023 · FY 2022

Source: USASpending.gov · refreshed Aug 16, 2026

Assistance listing 93.233 · National Center on Sleep Disorders Research

Real awards this federal program has made — the whole assistance listing (93.233), not just this notice.

No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.

Source: USASpending.gov · refreshed Aug 22, 2026

Assistance listing 93.273 · Alcohol Research Programs

Real awards this federal program has made — the whole assistance listing (93.273), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 100 $308,491 $157,932 – $601,291
FY 2025 175 $440,566 $194,934 – $1,114,948
FY 2024 237 $420,927 $153,632 – $1,110,810
FY 2023 327 $619,032 $350,328 – $1,806,361
FY 2022 314 $897,120 $369,477 – $2,547,224
FY 2021 274 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 1,427 — award counts are complete.

Who wins it Higher education (1,103), Nonprofit (187), Business (75) of 1,427 awards — categories can overlap.
Top states CA (118) · NC (58) · NY (57) · PA (41) · TX (40)
Largest recent awards
  1. THE JOHNS HOPKINS UNIVERSITY $36,249,682 · FY 2022
  2. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $9,079,530 · FY 2022
  3. BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA $6,335,676 · FY 2023
  4. VANDERBILT UNIVERSITY $5,361,769 · FY 2024
  5. LOHOCLA RESEARCH CORP $5,128,513 · FY 2022

Source: USASpending.gov · refreshed Aug 6, 2026

Assistance listing 93.279 · Drug Use and Addiction Research Programs

Real awards this federal program has made — the whole assistance listing (93.279), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 428 $422,523 $183,034 – $700,682
FY 2025 588 $709,054 $348,214 – $1,489,059
FY 2024 714 — —
FY 2023 724 — —
FY 2022 740 — —
FY 2021 606 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 3,800 — award counts are complete.

Who wins it Higher education (2,743), Nonprofit (534), Business (366) of 3,800 awards — categories can overlap.
Top states CA (130) · MA (90) · NY (86) · PA (72) · MD (56)
Largest recent awards
  1. FLORIDA INTERNATIONAL UNIVERSITY $7,372,834 · FY 2025
  2. BETH ISRAEL DEACONESS MEDICAL CENTER, INC. $7,081,684 · FY 2025
  3. UNIVERSITY OF WASHINGTON $7,003,822 · FY 2025
  4. REACX PHARMACEUTICALS, INC. $6,900,000 · FY 2025
  5. WORCESTER POLYTECHNIC INSTITUTE $6,889,914 · FY 2025

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.286 · Discovery and Applied Research for Technological Innovations to Improve Human Health

Real awards this federal program has made — the whole assistance listing (93.286), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 127 $276,000 $117,190 – $583,962
FY 2025 240 $555,997 $296,281 – $1,161,259
FY 2024 231 $589,216 $349,987 – $1,434,349
FY 2023 252 $652,889 $409,140 – $1,745,975
FY 2022 303 $691,306 $420,665 – $2,168,108
FY 2021 285 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 1,438 — award counts are complete.

Who wins it Higher education (1,055), Nonprofit (237), Business (99) of 1,438 awards — categories can overlap.
Top states CA (133) · MA (128) · NY (69) · PA (27) · NC (26)
Largest recent awards
  1. UNIVERSITY OF ILLINOIS $6,543,053 · FY 2022
  2. ALLEN INSTITUTE $6,281,935 · FY 2023
  3. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $5,888,124 · FY 2024
  4. WASHINGTON UNIVERSITY, THE $4,858,373 · FY 2024
  5. REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE $4,329,771 · FY 2023

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.310 · Trans-NIH Research Support

Real awards this federal program has made — the whole assistance listing (93.310), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 115 $582,838 $418,649 – $860,735
FY 2025 401 $786,876 $385,000 – $1,467,198
FY 2024 455 $1,174,898 $558,715 – $2,057,532
FY 2023 643 $1,437,358 $1,200,000 – $2,578,153
FY 2022 666 — —
FY 2021 689 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 2,969 — award counts are complete.

Who wins it Higher education (2,212), Nonprofit (582), Business (34) of 2,969 awards — categories can overlap.
Top states CA (153) · MA (103) · NY (93) · PA (63) · MI (21)
Largest recent awards
  1. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $34,424,926 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $33,014,143 · FY 2023
  3. MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION) $17,574,818 · FY 2024
  4. TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $16,308,508 · FY 2025
  5. UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $14,064,599 · FY 2025

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.313 · NIH Office of Research on Women's Health

Real awards this federal program has made — the whole assistance listing (93.313), not just this notice.

No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.

Source: USASpending.gov · refreshed Aug 30, 2026

Assistance listing 93.398 · Cancer Research Manpower

Real awards this federal program has made — the whole assistance listing (93.398), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 276 $54,054 $47,103 – $150,818
FY 2025 345 $123,409 $87,964 – $287,576
FY 2024 322 $223,327 $109,842 – $537,651
FY 2023 381 $632,297 $272,352 – $830,594
FY 2022 363 — —
FY 2021 443 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 2,130 — award counts are complete.

Who wins it Higher education (1,636), Nonprofit (428), State government (1) of 2,130 awards — categories can overlap.
Top states MA (131) · CA (118) · NY (112) · PA (61) · NC (44)
Largest recent awards
  1. UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL $4,313,330 · FY 2024
  2. NEW YORK UNIVERSITY $2,239,066 · FY 2023
  3. SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH $1,780,430 · FY 2023
  4. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $1,674,301 · FY 2024
  5. TRUSTEES OF INDIANA UNIVERSITY $1,480,091 · FY 2024

Source: USASpending.gov · refreshed Aug 22, 2026

Assistance listing 93.837 · Cardiovascular Diseases Research

Real awards this federal program has made — the whole assistance listing (93.837), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 910 $406,108 $121,423 – $769,962
FY 2025 1,358 $638,002 $257,444 – $1,262,955
FY 2024 1,513 — —
FY 2023 1,478 — —
FY 2022 1,536 — —
FY 2021 1,389 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 8,184 — award counts are complete.

Who wins it Higher education (5,706), Nonprofit (1,550), Business (596) of 8,184 awards — categories can overlap.
Top states CA (135) · MA (108) · NY (78) · PA (65) · OH (43)
Largest recent awards
  1. CHILDRENS HOSPITAL MEDICAL CENTER $6,452,040 · FY 2026
  2. KAISER FOUNDATION HOSPITALS $3,918,561 · FY 2025
  3. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $3,605,083 · FY 2026
  4. UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION $3,229,552 · FY 2026
  5. NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. $3,002,716 · FY 2026

Source: USASpending.gov · refreshed Aug 22, 2026

Assistance listing 93.838 · Lung Diseases Research

Real awards this federal program has made — the whole assistance listing (93.838), not just this notice.

No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.839 · Blood Diseases and Resources Research

Real awards this federal program has made — the whole assistance listing (93.839), not just this notice.

No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.840 · Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

Real awards this federal program has made — the whole assistance listing (93.840), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 0 — —
FY 2025 0 — —
FY 2024 1 $1,998,060 $1,998,060 – $1,998,060
FY 2023 8 $718,015 $520,326 – $1,181,909
FY 2022 0 — —
FY 2021 0 — —
Who wins it State government (4), Local government (3), Higher education (2) of 9 awards — categories can overlap.
Top states CA (1) · CO (1) · DE (1) · IN (1) · MI (1)
Largest recent awards
  1. MICHIGAN PUBLIC HEALTH INSTITUTE $1,332,220 · FY 2023
  2. INDIANA DEPARTMENT OF HEALTH $1,304,518 · FY 2023
  3. MINNESOTA DEPARTMENT OF HEALTH $1,141,039 · FY 2023
  4. SOUTHERN NEVADA HEALTH DIST $762,811 · FY 2023
  5. COUNTY OF CHARLESTON $673,219 · FY 2023

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.847 · Diabetes, Digestive, and Kidney Diseases Extramural Research

Real awards this federal program has made — the whole assistance listing (93.847), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 616 $537,141 $153,319 – $771,172
FY 2025 659 $730,832 $270,038 – $1,572,806
FY 2024 929 — —
FY 2023 961 — —
FY 2022 975 — —
FY 2021 1,012 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 5,152 — award counts are complete.

Who wins it Higher education (3,506), Nonprofit (1,046), Business (356) of 5,152 awards — categories can overlap.
Top states CA (137) · NY (98) · MA (84) · PA (74) · TX (64)
Largest recent awards
  1. BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE $6,282,406 · FY 2026
  2. THE LELAND STANFORD JUNIOR UNIVERSITY $5,583,712 · FY 2026
  3. RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA $5,180,852 · FY 2026
  4. NORTHWESTERN UNIVERSITY $4,764,127 · FY 2025
  5. UNIVERSITY OF SOUTH FLORIDA $4,640,761 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.865 · Child Health and Human Development Extramural Research

Real awards this federal program has made — the whole assistance listing (93.865), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 386 $392,826 $79,188 – $593,582
FY 2025 665 $452,972 $178,000 – $1,225,547
FY 2024 785 — —
FY 2023 835 — —
FY 2022 799 — —
FY 2021 764 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 4,234 — award counts are complete.

Who wins it Higher education (3,137), Nonprofit (693), Business (224) of 4,234 awards — categories can overlap.
Top states CA (103) · MA (87) · PA (75) · NY (62) · MI (34)
Largest recent awards
  1. PRESIDENT AND FELLOWS OF HARVARD COLLEGE $16,115,056 · FY 2025
  2. UNIVERSITY OF MIAMI $15,385,183 · FY 2025
  3. UNIVERSITY OF WASHINGTON $6,635,347 · FY 2025
  4. GEORGE WASHINGTON UNIVERSITY (THE) $5,117,920 · FY 2025
  5. RESEARCH TRIANGLE INSTITUTE $4,847,747 · FY 2025

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.866 · Aging Research

Real awards this federal program has made — the whole assistance listing (93.866), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 795 $493,972 $248,999 – $713,195
FY 2025 1,033 $643,089 $467,538 – $1,733,010
FY 2024 1,560 — —
FY 2023 1,539 — —
FY 2022 1,715 — —
FY 2021 1,595 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 8,237 — award counts are complete.

Who wins it Higher education (6,015), Nonprofit (1,370), Business (538) of 8,237 awards — categories can overlap.
Top states CA (153) · NY (110) · MA (100) · TX (57) · PA (41)
Largest recent awards
  1. REGENTS OF THE UNIVERSITY OF MICHIGAN $15,345,206 · FY 2026
  2. UNIVERSITY OF UTAH $10,793,501 · FY 2025
  3. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $10,223,348 · FY 2026
  4. SUTTER BAY HOSPITALS $9,466,491 · FY 2025
  5. TUFTS MEDICAL CENTER PARENT, INC. $8,296,115 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.879 · Medical Library Assistance

Real awards this federal program has made — the whole assistance listing (93.879), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 31 $349,875 $149,897 – $642,658
FY 2025 34 $614,550 $462,000 – $823,053
FY 2024 56 $485,250 $224,711 – $995,406
FY 2023 53 $727,873 $286,324 – $1,435,500
FY 2022 61 $812,919 $413,880 – $1,390,150
FY 2021 63 $1,329,473 $351,797 – $1,651,842
Who wins it Higher education (223), Nonprofit (41), Business (17) of 298 awards — categories can overlap.
Top states CA (43) · PA (32) · MA (23) · NY (22) · IL (9)
Largest recent awards
  1. UNIVERSITY OF UTAH $11,107,283 · FY 2021
  2. UNIVERSITY OF MARYLAND, BALTIMORE $10,600,468 · FY 2021
  3. UNIVERSITY OF WASHINGTON $6,868,908 · FY 2021
  4. THE MEDICAL UNIVERSITY OF SOUTH CAROLINA $6,810,297 · FY 2021
  5. THE UNIVERSITY OF IOWA $6,236,524 · FY 2021

Source: USASpending.gov · refreshed Aug 24, 2026