No. RFA-DA-26-034 · National Institutes of Health
Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)
- Award range
- Up to $300,000
- Expected awards
- Not specified
- Application deadline
- Nov 18, 2027
- Posted
- Nov 20, 2024
- Last verified
- 6 days ago
At a glance
AI summaryThis program funds basic research on the harmful effects of acute exposure to ultra-potent synthetic opioids such as fentanyl, carfentanil, and nitazenes, including mixtures like fentanyl and xylazine. It supports studies on the biological mechanisms of overdose, immediate and long-term health effects, and possible treatment or mitigation targets, but not clinical trials. Eligible applicants include many U.S. and nonprofit, for-profit, government, tribal, and foreign organizations, though foreign organizations and non-domestic components of U.S. organizations are not eligible to apply. NIH expects up to four awards totaling $2 million in FY 2026, with budgets limited to $300,000 in direct costs per year and project periods up to five years. No cost sharing is required.
AI-generated summary — verify against the announcement
What it funds
Official description from grants.gov
This notice of funding opportunity (NOFO) will support research towards understanding and mitigating the deleterious effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids (e.g., fentanyl, carfentanil, nitazenes) and their combinations (fentanyl and xylazine). This NOFO will also support research on the persistent and/or delayed pathophysiological effects after acute exposure to such agents.
Who can apply
- City or township governments
- County governments
- For-profit organizations other than small businesses
- Independent school districts
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Others
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities / Indian housing authorities
- Small businesses
- Special district governments
- State governments
Program history
USASpending.govAssistance listing 93.233 · National Center on Sleep Disorders Research
Real awards this federal program has made — the whole assistance listing (93.233), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 22, 2026
Assistance listing 93.279 · Drug Use and Addiction Research Programs
Real awards this federal program has made — the whole assistance listing (93.279), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 428 | $422,523 | $183,034 – $700,682 |
| FY 2025 | 588 | $709,054 | $348,214 – $1,489,059 |
| FY 2024 | 714 | — | — |
| FY 2023 | 724 | — | — |
| FY 2022 | 740 | — | — |
| FY 2021 | 606 | — | — |
For comparison, this notice advertises Up to $300,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 3,800 — award counts are complete.
- FLORIDA INTERNATIONAL UNIVERSITY $7,372,834 · FY 2025
- BETH ISRAEL DEACONESS MEDICAL CENTER, INC. $7,081,684 · FY 2025
- UNIVERSITY OF WASHINGTON $7,003,822 · FY 2025
- REACX PHARMACEUTICALS, INC. $6,900,000 · FY 2025
- WORCESTER POLYTECHNIC INSTITUTE $6,889,914 · FY 2025
Source: USASpending.gov · refreshed Aug 18, 2026
Assistance listing 93.837 · Cardiovascular Diseases Research
Real awards this federal program has made — the whole assistance listing (93.837), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 910 | $406,108 | $121,423 – $769,962 |
| FY 2025 | 1,358 | $638,002 | $257,444 – $1,262,955 |
| FY 2024 | 1,513 | — | — |
| FY 2023 | 1,478 | — | — |
| FY 2022 | 1,536 | — | — |
| FY 2021 | 1,389 | — | — |
For comparison, this notice advertises Up to $300,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 8,184 — award counts are complete.
- CHILDRENS HOSPITAL MEDICAL CENTER $6,452,040 · FY 2026
- KAISER FOUNDATION HOSPITALS $3,918,561 · FY 2025
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $3,605,083 · FY 2026
- UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION $3,229,552 · FY 2026
- NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. $3,002,716 · FY 2026
Source: USASpending.gov · refreshed Aug 22, 2026
Assistance listing 93.838 · Lung Diseases Research
Real awards this federal program has made — the whole assistance listing (93.838), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.839 · Blood Diseases and Resources Research
Real awards this federal program has made — the whole assistance listing (93.839), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.840 · Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
Real awards this federal program has made — the whole assistance listing (93.840), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 0 | — | — |
| FY 2025 | 0 | — | — |
| FY 2024 | 1 | $1,998,060 | $1,998,060 – $1,998,060 |
| FY 2023 | 8 | $718,015 | $520,326 – $1,181,909 |
| FY 2022 | 0 | — | — |
| FY 2021 | 0 | — | — |
For comparison, this notice advertises Up to $300,000.
- MICHIGAN PUBLIC HEALTH INSTITUTE $1,332,220 · FY 2023
- INDIANA DEPARTMENT OF HEALTH $1,304,518 · FY 2023
- MINNESOTA DEPARTMENT OF HEALTH $1,141,039 · FY 2023
- SOUTHERN NEVADA HEALTH DIST $762,811 · FY 2023
- COUNTY OF CHARLESTON $673,219 · FY 2023
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.855 · Allergy and Infectious Diseases Research
Real awards this federal program has made — the whole assistance listing (93.855), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 1,817 | $295,722 | $146,402 – $737,210 |
| FY 2025 | 1,596 | — | — |
| FY 2024 | 1,720 | — | — |
| FY 2023 | 1,711 | — | — |
| FY 2022 | 1,576 | — | — |
| FY 2021 | 1,857 | — | — |
For comparison, this notice advertises Up to $300,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 10,277 — award counts are complete.
- SCRIPPS RESEARCH INSTITUTE $3,679,976 · FY 2026
- REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $3,499,366 · FY 2026
- UNIVERSITY OF WASHINGTON $3,414,775 · FY 2026
- UNIVERSITY OF FLORIDA $3,389,992 · FY 2026
- ALBERT EINSTEIN COLLEGE OF MEDICINE $3,204,071 · FY 2026
Source: USASpending.gov · refreshed Aug 23, 2026