CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)

This program funds basic research on chemical threats that have primary or secondary effects on the nervous system, with the goal of understanding how these exposures cause toxicity and brain-related harm after a single acute exposure. Eligible applicants include U.S. higher education institutions, nonprofits, for-profit organizations, governments, tribal entities, faith-based and community organizations, regional organizations, and foreign organizations are not eligible to apply. NIH expects to make up to 4 awards totaling $2 million in FY 2026, with budgets capped at $300,000 in direct costs per year and project periods up to 3 years. No cost share is required, and clinical trials, efficacy studies, chronic exposure studies, opioid chemical threats, and chemicals not on the DHS chemical threat list are not responsive.

✳ AI-generated summary — verify against the announcement

• Health
• Research & Discovery
• Researchers & Scholars
• Biomedical & Disease Research
• Defense, National Security & Aerospace

• ✓ City or township governments
• ✓ County governments
• ✓ For-profit organizations other than small businesses
• ✓ Independent school districts
• ✓ Native American tribal governments (Federally recognized)
• ✓ Native American tribal organizations (other than Federally recognized)
• ✓ Nonprofits with 501(c)(3) status (other than higher education)
• ✓ Nonprofits without 501(c)(3) status (other than higher education)
• ✓ Others
• ✓ Private institutions of higher education
• ✓ Public and State controlled institutions of higher education
• ✓ Public housing authorities / Indian housing authorities
• ✓ Small businesses
• ✓ Special district governments
• ✓ State governments