Skip to content
Simpler Grants

No. RFA-DC-25-003 · National Institutes of Health

Open

Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)

grants.gov listing Full announcement (NOFO)
Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Funding Instrument Cooperative Agreement: A financial assistance mechanism used when there will be substantial Federal scientific or programmatic involvement.” — From the announcement
Award range
Up to $500,000
Expected awards
Not specified
Application deadline
Oct 1, 2026 29 days left
Posted
Jan 6, 2025
Last verified
6 days ago

At a glance

AI summary

This program funds investigator-initiated, higher-risk clinical trials using high-resolution in vivo imaging of the inner ear, including work to develop, improve, or translate imaging methods and related probes or contrast agents. Applications may be submitted by many kinds of organizations, including nonprofits, businesses, governments, and foreign organizations. NIDCD expects to fund 2 to 4 awards and plans to commit $3 million in FY 2025, with a maximum of less than $500,000 in direct costs per year unless prior approval is obtained. The maximum project period is 5 years, and no cost sharing is required.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Research & Discovery
  • Technology & Product Development
  • Patients & People with Health Conditions
  • Biomedical & Disease Research
Official description from grants.gov

This funding opportunity aims to support high risk clinical trials for the development of in vivo high-resolution structural and functional imaging technologies for the living human inner ear. Proposed projects should focus on improving the resolution of current imaging techniques or developing new imaging techniques that can visualize inner ear structures in vivo with significantly greater detail and accuracy than currently possible. Structural and functional aspects, including visualizing dynamic elements, are important to developing new and improved techniques. Projects may also focus on developing new imaging probes or contrast agents that can enhance visualization of the inner ear structures. Research supported in response to this RFA is expected to significantly advance the ability to visualize auditory and vestibular components, such as hair cells, otoliths, membranes, ions, and vasculature, in detail in awake patients in a clinical setting using non-invasive techniques. To achieve this goal, a multidisciplinary team approach that takes advantage of the expertise of each team member is highly encouraged. Studies in humans must be proposed to develop,advance, or test the needed technology. Any intermediate studies must articulate a clear path of the proposed methodology to application in awake humans or define the limitations and the usefulness in anesthetized humans.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.173 · Research Related to Deafness and Communication Disorders

Real awards this federal program has made — the whole assistance listing (93.173), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 170 $416,419 $134,042 – $648,731
FY 2025 238 $418,797 $187,647 – $1,008,401
FY 2024 283 $464,268 $152,978 – $1,268,772
FY 2023 260 $689,002 $272,758 – $1,868,608
FY 2022 286 $570,000 $145,264 – $2,113,099
FY 2021 246 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,483 — award counts are complete.

Who wins it Higher education (1,127), Nonprofit (192), Business (83) of 1,483 awards — categories can overlap.
Top states MA (107) · CA (101) · NY (89) · PA (78) · MD (30)
Largest recent awards
  1. REGENTS OF THE UNIVERSITY OF MINNESOTA $4,621,171 · FY 2022
  2. UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES $4,589,310 · FY 2023
  3. THE JOHNS HOPKINS UNIVERSITY $4,474,844 · FY 2022
  4. OREGON HEALTH & SCIENCE UNIVERSITY $3,863,432 · FY 2022
  5. THE LELAND STANFORD JUNIOR UNIVERSITY $3,579,023 · FY 2022

Source: USASpending.gov · refreshed Aug 16, 2026