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Simpler Grants

No. PAR-24-279 · National Institutes of Health

Open

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)

Dealbreakers No cost share required Audit: not stated Reimbursement-only: not stated
Award range
Not specified
Expected awards
Not specified
Application deadline
Nov 2, 2026
Posted
Dec 9, 2024
Last verified
5 days ago

At a glance

AI summary

This program funds short-term exploratory clinical trials for arthritis, musculoskeletal, and skin conditions or diseases, including early-stage studies such as first-in-human, dose-finding, safety, and biomarker studies. Applicants may be higher education institutions, nonprofits, governments, tribes, faith-based or community-based organizations, regional organizations, foreign organizations, and other eligible entities, but non-domestic non-U.S. entities and non-domestic components of U.S. organizations are not eligible; foreign components are allowed. The combined direct-cost budget for three years may not exceed $600,000, with no more than $300,000 in direct costs in any single year, and the project period may be up to three years. No cost sharing is required.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Research & Discovery
  • Patients & People with Health Conditions
  • Biomedical & Disease Research
Official description from grants.gov

This Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) PAR, a re-issue of PAR-24-035, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplify Review changes in Section V are the only changes that have been made. All other aspects of this funding opportunity remain the same.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.846 · Arthritis, Musculoskeletal and Skin Diseases Research

Real awards this federal program has made — the whole assistance listing (93.846), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 148 $377,506 $124,696 – $576,799
FY 2025 274 $432,326 $224,620 – $1,053,137
FY 2024 357 $473,099 $306,518 – $1,364,153
FY 2023 400 $611,188 $300,000 – $1,870,687
FY 2022 420
FY 2021 357

Dollar figures are based on the 1,000 most recent awards we store, not all 1,956 — award counts are complete.

Who wins it Higher education (1,364), Nonprofit (386), Business (144) of 1,956 awards — categories can overlap.
Top states CA (115) · MA (97) · NY (92) · PA (78) · NC (52)
Largest recent awards
  1. WAKE FOREST UNIVERSITY $10,449,074 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $5,795,791 · FY 2023
  3. REGENTS OF THE UNIVERSITY OF MICHIGAN $3,579,362 · FY 2023
  4. VANDERBILT UNIVERSITY MEDICAL CENTER $3,213,591 · FY 2026
  5. UNIVERSITY OF ALABAMA AT BIRMINGHAM $3,106,910 · FY 2023

Source: USASpending.gov · refreshed Aug 23, 2026