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Simpler Grants

No. PAR-24-280 · National Institutes of Health

Open

Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement
Award range
Not specified
Expected awards
Not specified
Application deadline
Nov 2, 2026
Posted
Dec 9, 2024
Last verified
5 days ago

At a glance

AI summary

This program funds clinical observational studies in musculoskeletal, rheumatic, and skin diseases, including studies that collect and analyze outcomes, biospecimens, images, and medical history data without changing treatment. It is for eligible U.S. and certain other organizations such as universities, nonprofits, governments, tribal organizations, faith-based groups, for-profits, and foreign organizations are not eligible to apply. Direct costs are limited to $475,000 over four years, with no more than $250,000 in any single year, and the number of awards depends on NIH appropriations and the quality of applications. No cost sharing is required. Only non-clinical-trial applications are allowed, and foreign components are permitted even though non-U.S. applicants and non-U.S. components of U.S. organizations are not eligible.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

This Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplified Review changes in Section V are the only changes that have been made. All other aspects of this funding opportunity remain the same.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.846 · Arthritis, Musculoskeletal and Skin Diseases Research

Real awards this federal program has made — the whole assistance listing (93.846), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 148 $377,506 $124,696 – $576,799
FY 2025 274 $432,326 $224,620 – $1,053,137
FY 2024 357 $473,099 $306,518 – $1,364,153
FY 2023 400 $611,188 $300,000 – $1,870,687
FY 2022 420
FY 2021 357

Dollar figures are based on the 1,000 most recent awards we store, not all 1,956 — award counts are complete.

Who wins it Higher education (1,364), Nonprofit (386), Business (144) of 1,956 awards — categories can overlap.
Top states CA (115) · MA (97) · NY (92) · PA (78) · NC (52)
Largest recent awards
  1. WAKE FOREST UNIVERSITY $10,449,074 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $5,795,791 · FY 2023
  3. REGENTS OF THE UNIVERSITY OF MICHIGAN $3,579,362 · FY 2023
  4. VANDERBILT UNIVERSITY MEDICAL CENTER $3,213,591 · FY 2026
  5. UNIVERSITY OF ALABAMA AT BIRMINGHAM $3,106,910 · FY 2023

Source: USASpending.gov · refreshed Aug 23, 2026