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Simpler Grants

No. PAR-25-296 · National Institutes of Health

Open

Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)

grants.gov listing Full announcement (NOFO)
Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Cooperative Agreement: A financial assistance mechanism used when there will be substantial Federal scientific or programmatic involvement.” — From the announcement
Award range
Up to $650,000
Expected awards
Not specified
Application deadline
Oct 19, 2027
Posted
Dec 11, 2024
Last verified
7 days ago

At a glance

AI summary

This program funds collaborative projects that develop, demonstrate, and spread innovative solutions to speed translational research across the CTSA Program and beyond. Eligible applicants include CTSA Program hubs and CTSA partnering institutions, and applications must fit the research interests of at least one participating NIH Institute, Center, or Office. The announcement does not state the number or size of awards or any cost-share requirement. Some topics have special scope limits, including NHGRI support for genomics tools for clinical trials, NIAID support for preclinical chemical countermeasure research only, and NIH institute-specific interests such as FDA regulatory science, NCATS data science and clinical trial innovation, and NIAMS disease-related translation.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Income Security and Social Services
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
  • Research Infrastructure, Instrumentation & Data
Official description from grants.gov

The CTSA Collaborative and Innovative Acceleration Award (CCIA) aims to accelerate the pace of translational research by supporting the collaborative development, dissemination, and sustainable implementation of innovative solutions across the CTSA Program Consortium and beyond. This Notice of Funding Opportunity (NOFO) invites investigator-initiated applications to develop, demonstrate, and disseminate innovative new approaches, technologies, resources, or models that increase the impact of research across diseases, transform the field of translational science, and bring more treatments for all people more quickly.

Who can apply

  • Public and State controlled institutions of higher education
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.121 · Oral Diseases and Disorders Research

Real awards this federal program has made — the whole assistance listing (93.121), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 155 $429,000 $306,500 – $571,863
FY 2025 277 $429,000 $310,295 – $829,259
FY 2024 301 $491,193 $310,985 – $1,283,003
FY 2023 320 $444,000 $298,673 – $1,756,575
FY 2022 295 — —
FY 2021 305 — —

For comparison, this notice advertises Up to $650,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,653 — award counts are complete.

Who wins it Higher education (1,224), Nonprofit (242), Business (71) of 1,653 awards — categories can overlap.
Top states CA (124) · PA (83) · MA (82) · NY (70) · TX (35)
Largest recent awards
  1. TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $6,128,166 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $4,961,133 · FY 2023
  3. RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK $4,002,156 · FY 2023
  4. DANA-FARBER CANCER INSTITUTE, INC. $3,742,682 · FY 2025
  5. TRUSTEES OF INDIANA UNIVERSITY $3,736,064 · FY 2023

Source: USASpending.gov · refreshed Aug 16, 2026

Assistance listing 93.172 · Human Genome Research

Real awards this federal program has made — the whole assistance listing (93.172), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 59 $719,909 $248,971 – $2,040,991
FY 2025 100 $491,802 $283,764 – $1,360,276
FY 2024 180 $737,013 $395,019 – $1,360,662
FY 2023 179 $766,801 $392,035 – $2,341,997
FY 2022 175 $894,953 $401,519 – $2,830,080
FY 2021 215 $1,999,233 $431,511 – $5,047,468

For comparison, this notice advertises Up to $650,000.

Who wins it Higher education (576), Nonprofit (196), Business (100) of 908 awards — categories can overlap.
Top states CA (163) · MA (125) · NY (103) · PA (43) · NC (17)
Largest recent awards
  1. BAYLOR COLLEGE OF MEDICINE $26,395,336 · FY 2021
  2. UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL $24,964,130 · FY 2021
  3. THE LELAND STANFORD JUNIOR UNIVERSITY $22,977,417 · FY 2021
  4. THE BROAD INSTITUTE, INC $22,339,977 · FY 2021
  5. JACKSON LABORATORY $21,311,202 · FY 2021

Source: USASpending.gov · refreshed Aug 16, 2026

Assistance listing 93.307 · Minority Health and Health Disparities Research

Real awards this federal program has made — the whole assistance listing (93.307), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 40 $768,076 $248,928 – $851,492
FY 2025 57 $604,863 $333,504 – $1,512,644
FY 2024 182 $465,783 $308,121 – $1,983,267
FY 2023 212 $1,299,549 $438,782 – $2,594,510
FY 2022 249 $1,408,033 $444,695 – $2,988,012
FY 2021 168 $2,071,562 $431,619 – $3,273,896

For comparison, this notice advertises Up to $650,000.

Who wins it Higher education (660), Nonprofit (111), Business (97) of 908 awards — categories can overlap.
Top states CA (114) · NY (92) · MA (45) · TX (45) · PA (26)
Largest recent awards
  1. UNIVERSITY OF CALIFORNIA, SAN DIEGO $40,426,614 · FY 2021
  2. UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL $30,744,792 · FY 2021
  3. CHILDREN'S HOSPITAL LOS ANGELES $27,816,472 · FY 2021
  4. UNIVERSITY OF ALABAMA AT BIRMINGHAM $27,671,310 · FY 2021
  5. REGENTS OF THE UNIVERSITY OF MINNESOTA $24,809,662 · FY 2021

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.313 · NIH Office of Research on Women's Health

Real awards this federal program has made — the whole assistance listing (93.313), not just this notice.

No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.

Source: USASpending.gov · refreshed Aug 30, 2026

Assistance listing 93.350 · National Center for Advancing Translational Sciences

Real awards this federal program has made — the whole assistance listing (93.350), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 106 $427,386 $166,500 – $755,137
FY 2025 110 $427,602 $178,000 – $1,833,042
FY 2024 137 $463,150 $176,720 – $2,139,478
FY 2023 131 $363,189 $155,500 – $3,024,000
FY 2022 106 $438,741 $156,117 – $1,906,971
FY 2021 76 $324,197 $28,713 – $1,276,814

For comparison, this notice advertises Up to $650,000.

Who wins it Higher education (344), Business (161), Nonprofit (137) of 666 awards — categories can overlap.
Top states CA (74) · NY (48) · NC (38) · MA (36) · PA (28)
Largest recent awards
  1. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $46,369,962 · FY 2022
  2. TRUSTEES OF TUFTS COLLEGE $44,451,810 · FY 2023
  3. PRESIDENT AND FELLOWS OF HARVARD COLLEGE $43,319,327 · FY 2023
  4. REGENTS OF THE UNIVERSITY OF MICHIGAN $39,816,036 · FY 2023
  5. THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER $39,349,638 · FY 2021

Source: USASpending.gov · refreshed Aug 30, 2026

Assistance listing 93.846 · Arthritis, Musculoskeletal and Skin Diseases Research

Real awards this federal program has made — the whole assistance listing (93.846), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 148 $377,506 $124,696 – $576,799
FY 2025 274 $432,326 $224,620 – $1,053,137
FY 2024 357 $473,099 $306,518 – $1,364,153
FY 2023 400 $611,188 $300,000 – $1,870,687
FY 2022 420 — —
FY 2021 357 — —

For comparison, this notice advertises Up to $650,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,956 — award counts are complete.

Who wins it Higher education (1,364), Nonprofit (386), Business (144) of 1,956 awards — categories can overlap.
Top states CA (115) · MA (97) · NY (92) · PA (78) · NC (52)
Largest recent awards
  1. WAKE FOREST UNIVERSITY $10,449,074 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $5,795,791 · FY 2023
  3. REGENTS OF THE UNIVERSITY OF MICHIGAN $3,579,362 · FY 2023
  4. VANDERBILT UNIVERSITY MEDICAL CENTER $3,213,591 · FY 2026
  5. UNIVERSITY OF ALABAMA AT BIRMINGHAM $3,106,910 · FY 2023

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.855 · Allergy and Infectious Diseases Research

Real awards this federal program has made — the whole assistance listing (93.855), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 1,817 $295,722 $146,402 – $737,210
FY 2025 1,596 — —
FY 2024 1,720 — —
FY 2023 1,711 — —
FY 2022 1,576 — —
FY 2021 1,857 — —

For comparison, this notice advertises Up to $650,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 10,277 — award counts are complete.

Who wins it Higher education (7,336), Nonprofit (1,735), Business (694) of 10,277 awards — categories can overlap.
Top states CA (122) · MA (85) · NY (78) · PA (69) · TX (47)
Largest recent awards
  1. SCRIPPS RESEARCH INSTITUTE $3,679,976 · FY 2026
  2. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $3,499,366 · FY 2026
  3. UNIVERSITY OF WASHINGTON $3,414,775 · FY 2026
  4. UNIVERSITY OF FLORIDA $3,389,992 · FY 2026
  5. ALBERT EINSTEIN COLLEGE OF MEDICINE $3,204,071 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.859 · Biomedical Research and Research Training

Real awards this federal program has made — the whole assistance listing (93.859), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 1,048 $420,000 $325,870 – $487,506
FY 2025 1,115 — —
FY 2024 1,171 — —
FY 2023 1,383 — —
FY 2022 1,574 — —
FY 2021 1,321 — —

For comparison, this notice advertises Up to $650,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 7,612 — award counts are complete.

Who wins it Higher education (6,024), Nonprofit (734), Business (565) of 7,612 awards — categories can overlap.
Top states CA (149) · NY (81) · TX (73) · PA (60) · MA (55)
Largest recent awards
  1. UNIVERSITY OF MISSISSIPPI MEDICAL CENTER $5,185,402 · FY 2026
  2. UNIVERSITY OF WISCONSIN SYSTEM $3,654,310 · FY 2026
  3. THE TRUSTEES OF PRINCETON UNIVERSITY $2,993,000 · FY 2026
  4. BATTELLE MEMORIAL INSTITUTE $2,843,142 · FY 2026
  5. UNIVERSITY OF LOUISVILLE $2,652,150 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.865 · Child Health and Human Development Extramural Research

Real awards this federal program has made — the whole assistance listing (93.865), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 386 $392,826 $79,188 – $593,582
FY 2025 665 $452,972 $178,000 – $1,225,547
FY 2024 785 — —
FY 2023 835 — —
FY 2022 799 — —
FY 2021 764 — —

For comparison, this notice advertises Up to $650,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 4,234 — award counts are complete.

Who wins it Higher education (3,137), Nonprofit (693), Business (224) of 4,234 awards — categories can overlap.
Top states CA (103) · MA (87) · PA (75) · NY (62) · MI (34)
Largest recent awards
  1. PRESIDENT AND FELLOWS OF HARVARD COLLEGE $16,115,056 · FY 2025
  2. UNIVERSITY OF MIAMI $15,385,183 · FY 2025
  3. UNIVERSITY OF WASHINGTON $6,635,347 · FY 2025
  4. GEORGE WASHINGTON UNIVERSITY (THE) $5,117,920 · FY 2025
  5. RESEARCH TRIANGLE INSTITUTE $4,847,747 · FY 2025

Source: USASpending.gov · refreshed Aug 23, 2026