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Simpler Grants

No. PA-25-302 · National Institutes of Health

Open

NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

grants.gov listing Full announcement (NOFO)
Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement
Award range
Up to $50,000
Expected awards
Not specified
Application deadline
Jan 7, 2028
Posted
Dec 18, 2024
Last verified
8 days ago

At a glance

AI summary

This NIH program funds small, well-defined research projects that can be completed in two years, including pilot studies, secondary analysis of existing data, small self-contained projects, research methods development, and new research technology development. Eligible applicants include a wide range of organizations, including nonprofits, higher education institutions, governments, small businesses, foreign organizations, and other U.S. and non-U.S. entities; foreign components are also allowed. Application budgets are limited to $50,000 in direct costs per year, the project period may not exceed two years, and the number of awards depends on NIH appropriations and the quality of applications. Cost sharing is not required, and clinical trials are not allowed.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Environment
  • Health
  • Income Security and Social Services
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.113 · Environmental Health

Real awards this federal program has made — the whole assistance listing (93.113), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 149 $379,262 $119,524 – $644,459
FY 2025 210 $431,750 $254,376 – $1,187,118
FY 2024 281 $583,878 $300,000 – $1,672,899
FY 2023 242 $587,197 $216,320 – $1,842,227
FY 2022 258 $465,538 $259,613 – $2,117,638
FY 2021 239 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,379 — award counts are complete.

Who wins it Higher education (1,027), Nonprofit (157), Business (146) of 1,379 awards — categories can overlap.
Top states CA (132) · NY (120) · MA (87) · NC (66) · TX (40)
Largest recent awards
  1. VANDERBILT UNIVERSITY MEDICAL CENTER $32,769,976 · FY 2023
  2. NORTH CAROLINA STATE UNIVERSITY $10,038,112 · FY 2023
  3. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $9,460,610 · FY 2022
  4. THE JOHNS HOPKINS UNIVERSITY $9,120,320 · FY 2022
  5. TRUSTEES OF BOSTON UNIVERSITY $8,944,898 · FY 2023

Source: USASpending.gov · refreshed Aug 16, 2026

Assistance listing 93.143 · NIEHS Superfund Hazardous Substances_Basic Research and Education

Real awards this federal program has made — the whole assistance listing (93.143), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 4 $1,618,209 $140,007 – $3,350,156
FY 2025 4 $614,200 $176,034 – $2,005,416
FY 2024 12 $108,169 $23,725 – $174,673
FY 2023 7 $173,075 $98,548 – $781,558
FY 2022 13 $422,125 $50,000 – $1,138,687
FY 2021 25 $1,123,317 $168,087 – $1,247,726

For comparison, this notice advertises Up to $50,000.

Who wins it Higher education (39), Business (21), Nonprofit (2) of 65 awards — categories can overlap.
Top states CA (8) · LA (5) · MO (4) · MD (3) · NC (3)
Largest recent awards
  1. WAYNE STATE UNIVERSITY $11,442,926 · FY 2022
  2. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $9,923,739 · FY 2022
  3. YALE UNIV $7,718,009 · FY 2022
  4. UNIVERSITY OF SOUTHERN CALIFORNIA $4,901,863 · FY 2025
  5. NORTH CAROLINA STATE UNIVERSITY $4,233,899 · FY 2026

Source: USASpending.gov · refreshed Aug 16, 2026

Assistance listing 93.172 · Human Genome Research

Real awards this federal program has made — the whole assistance listing (93.172), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 59 $719,909 $248,971 – $2,040,991
FY 2025 100 $491,802 $283,764 – $1,360,276
FY 2024 180 $737,013 $395,019 – $1,360,662
FY 2023 179 $766,801 $392,035 – $2,341,997
FY 2022 175 $894,953 $401,519 – $2,830,080
FY 2021 215 $1,999,233 $431,511 – $5,047,468

For comparison, this notice advertises Up to $50,000.

Who wins it Higher education (576), Nonprofit (196), Business (100) of 908 awards — categories can overlap.
Top states CA (163) · MA (125) · NY (103) · PA (43) · NC (17)
Largest recent awards
  1. BAYLOR COLLEGE OF MEDICINE $26,395,336 · FY 2021
  2. UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL $24,964,130 · FY 2021
  3. THE LELAND STANFORD JUNIOR UNIVERSITY $22,977,417 · FY 2021
  4. THE BROAD INSTITUTE, INC $22,339,977 · FY 2021
  5. JACKSON LABORATORY $21,311,202 · FY 2021

Source: USASpending.gov · refreshed Aug 16, 2026

Assistance listing 93.233 · National Center on Sleep Disorders Research

Real awards this federal program has made — the whole assistance listing (93.233), not just this notice.

No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.

Source: USASpending.gov · refreshed Aug 22, 2026

Assistance listing 93.242 · Mental Health Research Grants

Real awards this federal program has made — the whole assistance listing (93.242), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 491 $451,000 $167,702 – $811,948
FY 2025 600 $731,738 $320,544 – $1,460,736
FY 2024 883 — —
FY 2023 898 — —
FY 2022 986 — —
FY 2021 945 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 4,803 — award counts are complete.

Who wins it Higher education (3,532), Nonprofit (816), Business (215) of 4,803 awards — categories can overlap.
Top states CA (166) · NY (127) · MA (104) · PA (79) · IL (22)
Largest recent awards
  1. MASSACHUSETTS INSTITUTE OF TECHNOLOGY $21,714,815 · FY 2025
  2. OHIO STATE UNIVERSITY, THE $19,515,757 · FY 2025
  3. ALBERT EINSTEIN COLLEGE OF MEDICINE $18,270,924 · FY 2025
  4. DUKE UNIVERSITY $15,039,330 · FY 2025
  5. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $12,007,972 · FY 2026

Source: USASpending.gov · refreshed Aug 6, 2026

Assistance listing 93.273 · Alcohol Research Programs

Real awards this federal program has made — the whole assistance listing (93.273), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 100 $308,491 $157,932 – $601,291
FY 2025 175 $440,566 $194,934 – $1,114,948
FY 2024 237 $420,927 $153,632 – $1,110,810
FY 2023 327 $619,032 $350,328 – $1,806,361
FY 2022 314 $897,120 $369,477 – $2,547,224
FY 2021 274 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,427 — award counts are complete.

Who wins it Higher education (1,103), Nonprofit (187), Business (75) of 1,427 awards — categories can overlap.
Top states CA (118) · NC (58) · NY (57) · PA (41) · TX (40)
Largest recent awards
  1. THE JOHNS HOPKINS UNIVERSITY $36,249,682 · FY 2022
  2. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $9,079,530 · FY 2022
  3. BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA $6,335,676 · FY 2023
  4. VANDERBILT UNIVERSITY $5,361,769 · FY 2024
  5. LOHOCLA RESEARCH CORP $5,128,513 · FY 2022

Source: USASpending.gov · refreshed Aug 6, 2026

Assistance listing 93.279 · Drug Use and Addiction Research Programs

Real awards this federal program has made — the whole assistance listing (93.279), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 428 $422,523 $183,034 – $700,682
FY 2025 588 $709,054 $348,214 – $1,489,059
FY 2024 714 — —
FY 2023 724 — —
FY 2022 740 — —
FY 2021 606 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 3,800 — award counts are complete.

Who wins it Higher education (2,743), Nonprofit (534), Business (366) of 3,800 awards — categories can overlap.
Top states CA (130) · MA (90) · NY (86) · PA (72) · MD (56)
Largest recent awards
  1. FLORIDA INTERNATIONAL UNIVERSITY $7,372,834 · FY 2025
  2. BETH ISRAEL DEACONESS MEDICAL CENTER, INC. $7,081,684 · FY 2025
  3. UNIVERSITY OF WASHINGTON $7,003,822 · FY 2025
  4. REACX PHARMACEUTICALS, INC. $6,900,000 · FY 2025
  5. WORCESTER POLYTECHNIC INSTITUTE $6,889,914 · FY 2025

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.286 · Discovery and Applied Research for Technological Innovations to Improve Human Health

Real awards this federal program has made — the whole assistance listing (93.286), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 127 $276,000 $117,190 – $583,962
FY 2025 240 $555,997 $296,281 – $1,161,259
FY 2024 231 $589,216 $349,987 – $1,434,349
FY 2023 252 $652,889 $409,140 – $1,745,975
FY 2022 303 $691,306 $420,665 – $2,168,108
FY 2021 285 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,438 — award counts are complete.

Who wins it Higher education (1,055), Nonprofit (237), Business (99) of 1,438 awards — categories can overlap.
Top states CA (133) · MA (128) · NY (69) · PA (27) · NC (26)
Largest recent awards
  1. UNIVERSITY OF ILLINOIS $6,543,053 · FY 2022
  2. ALLEN INSTITUTE $6,281,935 · FY 2023
  3. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $5,888,124 · FY 2024
  4. WASHINGTON UNIVERSITY, THE $4,858,373 · FY 2024
  5. REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE $4,329,771 · FY 2023

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.310 · Trans-NIH Research Support

Real awards this federal program has made — the whole assistance listing (93.310), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 115 $582,838 $418,649 – $860,735
FY 2025 401 $786,876 $385,000 – $1,467,198
FY 2024 455 $1,174,898 $558,715 – $2,057,532
FY 2023 643 $1,437,358 $1,200,000 – $2,578,153
FY 2022 666 — —
FY 2021 689 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 2,969 — award counts are complete.

Who wins it Higher education (2,212), Nonprofit (582), Business (34) of 2,969 awards — categories can overlap.
Top states CA (153) · MA (103) · NY (93) · PA (63) · MI (21)
Largest recent awards
  1. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $34,424,926 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $33,014,143 · FY 2023
  3. MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION) $17,574,818 · FY 2024
  4. TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $16,308,508 · FY 2025
  5. UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $14,064,599 · FY 2025

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.837 · Cardiovascular Diseases Research

Real awards this federal program has made — the whole assistance listing (93.837), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 910 $406,108 $121,423 – $769,962
FY 2025 1,358 $638,002 $257,444 – $1,262,955
FY 2024 1,513 — —
FY 2023 1,478 — —
FY 2022 1,536 — —
FY 2021 1,389 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 8,184 — award counts are complete.

Who wins it Higher education (5,706), Nonprofit (1,550), Business (596) of 8,184 awards — categories can overlap.
Top states CA (135) · MA (108) · NY (78) · PA (65) · OH (43)
Largest recent awards
  1. CHILDRENS HOSPITAL MEDICAL CENTER $6,452,040 · FY 2026
  2. KAISER FOUNDATION HOSPITALS $3,918,561 · FY 2025
  3. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $3,605,083 · FY 2026
  4. UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION $3,229,552 · FY 2026
  5. NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. $3,002,716 · FY 2026

Source: USASpending.gov · refreshed Aug 22, 2026

Assistance listing 93.838 · Lung Diseases Research

Real awards this federal program has made — the whole assistance listing (93.838), not just this notice.

No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.839 · Blood Diseases and Resources Research

Real awards this federal program has made — the whole assistance listing (93.839), not just this notice.

No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.840 · Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

Real awards this federal program has made — the whole assistance listing (93.840), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 0 — —
FY 2025 0 — —
FY 2024 1 $1,998,060 $1,998,060 – $1,998,060
FY 2023 8 $718,015 $520,326 – $1,181,909
FY 2022 0 — —
FY 2021 0 — —

For comparison, this notice advertises Up to $50,000.

Who wins it State government (4), Local government (3), Higher education (2) of 9 awards — categories can overlap.
Top states CA (1) · CO (1) · DE (1) · IN (1) · MI (1)
Largest recent awards
  1. MICHIGAN PUBLIC HEALTH INSTITUTE $1,332,220 · FY 2023
  2. INDIANA DEPARTMENT OF HEALTH $1,304,518 · FY 2023
  3. MINNESOTA DEPARTMENT OF HEALTH $1,141,039 · FY 2023
  4. SOUTHERN NEVADA HEALTH DIST $762,811 · FY 2023
  5. COUNTY OF CHARLESTON $673,219 · FY 2023

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.853 · Extramural Research Programs in the Neurosciences and Neurological Disorders

Real awards this federal program has made — the whole assistance listing (93.853), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 654 $405,461 $120,825 – $587,738
FY 2025 923 $491,085 $157,949 – $1,077,840
FY 2024 1,031 — —
FY 2023 1,194 — —
FY 2022 1,228 — —
FY 2021 1,132 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 6,162 — award counts are complete.

Who wins it Higher education (4,669), Nonprofit (990), Business (259) of 6,162 awards — categories can overlap.
Top states CA (153) · NY (99) · MA (93) · PA (74) · TX (39)
Largest recent awards
  1. THE LELAND STANFORD JUNIOR UNIVERSITY $5,747,701 · FY 2025
  2. YALE UNIV $4,888,497 · FY 2025
  3. MAYO CLINIC $3,746,535 · FY 2026
  4. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $3,153,019 · FY 2025
  5. UNIVERSITY OF CALIFORNIA, LOS ANGELES $3,109,857 · FY 2025

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.855 · Allergy and Infectious Diseases Research

Real awards this federal program has made — the whole assistance listing (93.855), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 1,817 $295,722 $146,402 – $737,210
FY 2025 1,596 — —
FY 2024 1,720 — —
FY 2023 1,711 — —
FY 2022 1,576 — —
FY 2021 1,857 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 10,277 — award counts are complete.

Who wins it Higher education (7,336), Nonprofit (1,735), Business (694) of 10,277 awards — categories can overlap.
Top states CA (122) · MA (85) · NY (78) · PA (69) · TX (47)
Largest recent awards
  1. SCRIPPS RESEARCH INSTITUTE $3,679,976 · FY 2026
  2. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $3,499,366 · FY 2026
  3. UNIVERSITY OF WASHINGTON $3,414,775 · FY 2026
  4. UNIVERSITY OF FLORIDA $3,389,992 · FY 2026
  5. ALBERT EINSTEIN COLLEGE OF MEDICINE $3,204,071 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.865 · Child Health and Human Development Extramural Research

Real awards this federal program has made — the whole assistance listing (93.865), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 386 $392,826 $79,188 – $593,582
FY 2025 665 $452,972 $178,000 – $1,225,547
FY 2024 785 — —
FY 2023 835 — —
FY 2022 799 — —
FY 2021 764 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 4,234 — award counts are complete.

Who wins it Higher education (3,137), Nonprofit (693), Business (224) of 4,234 awards — categories can overlap.
Top states CA (103) · MA (87) · PA (75) · NY (62) · MI (34)
Largest recent awards
  1. PRESIDENT AND FELLOWS OF HARVARD COLLEGE $16,115,056 · FY 2025
  2. UNIVERSITY OF MIAMI $15,385,183 · FY 2025
  3. UNIVERSITY OF WASHINGTON $6,635,347 · FY 2025
  4. GEORGE WASHINGTON UNIVERSITY (THE) $5,117,920 · FY 2025
  5. RESEARCH TRIANGLE INSTITUTE $4,847,747 · FY 2025

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.866 · Aging Research

Real awards this federal program has made — the whole assistance listing (93.866), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 795 $493,972 $248,999 – $713,195
FY 2025 1,033 $643,089 $467,538 – $1,733,010
FY 2024 1,560 — —
FY 2023 1,539 — —
FY 2022 1,715 — —
FY 2021 1,595 — —

For comparison, this notice advertises Up to $50,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 8,237 — award counts are complete.

Who wins it Higher education (6,015), Nonprofit (1,370), Business (538) of 8,237 awards — categories can overlap.
Top states CA (153) · NY (110) · MA (100) · TX (57) · PA (41)
Largest recent awards
  1. REGENTS OF THE UNIVERSITY OF MICHIGAN $15,345,206 · FY 2026
  2. UNIVERSITY OF UTAH $10,793,501 · FY 2025
  3. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $10,223,348 · FY 2026
  4. SUTTER BAY HOSPITALS $9,466,491 · FY 2025
  5. TUFTS MEDICAL CENTER PARENT, INC. $8,296,115 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.879 · Medical Library Assistance

Real awards this federal program has made — the whole assistance listing (93.879), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 31 $349,875 $149,897 – $642,658
FY 2025 34 $614,550 $462,000 – $823,053
FY 2024 56 $485,250 $224,711 – $995,406
FY 2023 53 $727,873 $286,324 – $1,435,500
FY 2022 61 $812,919 $413,880 – $1,390,150
FY 2021 63 $1,329,473 $351,797 – $1,651,842

For comparison, this notice advertises Up to $50,000.

Who wins it Higher education (223), Nonprofit (41), Business (17) of 298 awards — categories can overlap.
Top states CA (43) · PA (32) · MA (23) · NY (22) · IL (9)
Largest recent awards
  1. UNIVERSITY OF UTAH $11,107,283 · FY 2021
  2. UNIVERSITY OF MARYLAND, BALTIMORE $10,600,468 · FY 2021
  3. UNIVERSITY OF WASHINGTON $6,868,908 · FY 2021
  4. THE MEDICAL UNIVERSITY OF SOUTH CAROLINA $6,810,297 · FY 2021
  5. THE UNIVERSITY OF IOWA $6,236,524 · FY 2021

Source: USASpending.gov · refreshed Aug 24, 2026