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Simpler Grants

No. PAR-25-155 · National Institutes of Health

Open

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)

Dealbreakers No cost share required Audit: not stated Reimbursement-only: not stated
Invitation only
“This is a limited competition.” — From the announcement
Award range
Up to $50,000
Expected awards
Not specified
Application deadline
Oct 19, 2026
Posted
Dec 11, 2024
Last verified
Today

At a glance

AI summary

This program supports small, self-contained translational science research projects that address roadblocks in science or operations and develop, demonstrate, or share innovative solutions. It is limited to NCATS CTSA Program KL2/K12 scholars who received direct NCATS funding and completed the training program, and applications must be submitted within 2 years of finishing the appointment. Awards provide up to $50,000 in direct costs per year for up to 2 years, and no cost sharing is required. Foreign organizations and non-U.S. components of U.S. organizations are not eligible, but foreign components are allowed. Clinical trials are optional, and NCATS does not support trials beyond Phase IIB except Phase III trials for rare diseases or conditions.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of re-entry supplements supported by the CTSA Program to conduct research as they complete the transition to fully independent academic translational scientists. These R03 grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Research proposed in the R03 application may or may not include patient-oriented research. The R03 is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that provide preliminary data to support submission of a subsequent R01, or equivalent, application.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.350 · National Center for Advancing Translational Sciences

Real awards this federal program has made — the whole assistance listing (93.350), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 106 $427,386 $166,500 – $755,137
FY 2025 110 $427,602 $178,000 – $1,833,042
FY 2024 137 $463,150 $176,720 – $2,139,478
FY 2023 131 $363,189 $155,500 – $3,024,000
FY 2022 106 $438,741 $156,117 – $1,906,971
FY 2021 76 $324,197 $28,713 – $1,276,814

For comparison, this notice advertises Up to $50,000.

Who wins it Higher education (344), Business (161), Nonprofit (137) of 666 awards — categories can overlap.
Top states CA (74) · NY (48) · NC (38) · MA (36) · PA (28)
Largest recent awards
  1. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $46,369,962 · FY 2022
  2. TRUSTEES OF TUFTS COLLEGE $44,451,810 · FY 2023
  3. PRESIDENT AND FELLOWS OF HARVARD COLLEGE $43,319,327 · FY 2023
  4. REGENTS OF THE UNIVERSITY OF MICHIGAN $39,816,036 · FY 2023
  5. THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER $39,349,638 · FY 2021

Source: USASpending.gov · refreshed Aug 30, 2026