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Simpler Grants

No. PAR-25-104 · National Institutes of Health

Open

Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional)

grants.gov listing Full announcement (NOFO)
Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement
Award range
Not specified
Expected awards
Not specified
Application deadline
Oct 25, 2027
Posted
Nov 5, 2024
Last verified
Yesterday

At a glance

AI summary

This grant supports planning studies needed to complete the protocol for a future multi-center Phase II or later cancer prevention or control clinical trial. Applicants may be nonprofits, universities, governments, for-profits, small businesses, tribal organizations, faith-based or community organizations, and foreign organizations, and the award is for up to three years. Budgets are limited to $225,000 per year, with up to $450,000 in direct costs over three years if no pilot/feasibility trial is included, or up to $600,000 if a pilot/feasibility clinical trial is included. No cost sharing is required. Applications must address topics within the mission of the NIH cancer prevention and control divisions, and first-in-human studies, purely mechanistic or animal studies, and applications without preliminary efficacy or effectiveness data are not responsive.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Health
  • Planning & Coordination
  • Research & Discovery
  • Patients & People with Health Conditions
  • Researchers & Scholars
  • Biomedical & Disease Research
  • Health Care Delivery, Access & Workforce
  • Public Health, Prevention & Nutrition
Official description from grants.gov

The purpose of this FOA is to facilitate well planned clinical trials across the cancer prevention and control spectrum aimed at improving prevention/ interception, cancer-related health behaviors, screening, early detection, healthcare delivery, management of treatment-related symptoms, supportive care, and the long-term outcomes of cancer survivors. Although the scientific literature or preliminary data may provide the rationale for conducting a clinical trial, investigators often lack critical information about the study population, accrual challenges, intervention, outcome/ endpoints, data/statistical challenges or operational risks necessary to finalize the trial protocol completely. These information gaps can result in multiple protocol changes before and after trial start-up, leading to the need for additional time and expenses that may prevent study completion. Further, the suitability and feasibility of new trial designs, which minimize infrastructure and reduce costs may need to be tested in the context of a particular intervention, at-risk group, symptom or venue. Preparatory studies may fill information gaps and address unknowns, improving trial design and knowledge of trial feasibility and thus saving NCI time and money.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.399 · Cancer Control

Real awards this federal program has made — the whole assistance listing (93.399), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 0 — —
FY 2025 1 $2,490,206 $2,490,206 – $2,490,206
FY 2024 13 $3,165,783 $804,361 – $3,227,950
FY 2023 7 $1,121,797 $947,583 – $1,353,065
FY 2022 14 $4,573,965 $2,523,875 – $6,154,995
FY 2021 5 $3,186,801 $2,957,140 – $3,199,301
Who wins it Higher education (28), Nonprofit (8) of 40 awards — categories can overlap.
Top states CA (5) · WA (5) · MI (3) · NY (3) · GA (2)
Largest recent awards
  1. UNIVERSITY OF DELAWARE $16,730,455 · FY 2021
  2. VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY $8,183,001 · FY 2022
  3. FRED HUTCHINSON CANCER CENTER $7,696,898 · FY 2022
  4. THE INSTITUTE FOR CANCER RESEARCH $6,471,989 · FY 2022
  5. WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY $4,655,326 · FY 2022

Source: USASpending.gov · refreshed Aug 22, 2026