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Simpler Grants

No. PAR-25-149 · National Institutes of Health

Open

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Cooperative Agreement: A financial assistance mechanism” — From the announcement
Invitation only
“This is a limited competition.” — From the announcement
Award range
Not specified
Expected awards
Not specified
Application deadline
Nov 5, 2027
Posted
Oct 28, 2024
Last verified
3 days ago

At a glance

AI summary

This notice supports renewal applications for existing NINDS-funded clinical trial cooperative agreements (U01) that need more time and funds to finish an active trial. Only institutions with current NINDS U01 awards originally funded under the listed NINDS or NIH StrokeNet announcements may apply, and the application must include a clinical trial. The number of awards depends on NIH funding and the number of meritorious applications, and budgets are not capped but must match the project’s actual needs; the maximum project period is 5 years. No cost sharing is required. Foreign organizations are not eligible to apply, although foreign components of U.S. organizations are allowed.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

This limited competition Notice of Funding Opportunity (NOFO) invites renewal applications of existing NINDS-supported clinical trial cooperative agreement awards (U01) requiring additional time and resources to complete the clinical trial.

Who can apply

  • Independent school districts
  • Others
  • Public housing authorities / Indian housing authorities
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.853 · Extramural Research Programs in the Neurosciences and Neurological Disorders

Real awards this federal program has made — the whole assistance listing (93.853), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 654 $405,461 $120,825 – $587,738
FY 2025 923 $491,085 $157,949 – $1,077,840
FY 2024 1,031
FY 2023 1,194
FY 2022 1,228
FY 2021 1,132

Dollar figures are based on the 1,000 most recent awards we store, not all 6,162 — award counts are complete.

Who wins it Higher education (4,669), Nonprofit (990), Business (259) of 6,162 awards — categories can overlap.
Top states CA (153) · NY (99) · MA (93) · PA (74) · TX (39)
Largest recent awards
  1. THE LELAND STANFORD JUNIOR UNIVERSITY $5,747,701 · FY 2025
  2. YALE UNIV $4,888,497 · FY 2025
  3. MAYO CLINIC $3,746,535 · FY 2026
  4. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $3,153,019 · FY 2025
  5. UNIVERSITY OF CALIFORNIA, LOS ANGELES $3,109,857 · FY 2025

Source: USASpending.gov · refreshed Aug 23, 2026