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Simpler Grants

No. PAR-27-058 · National Institutes of Health

Open

NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)

grants.gov listing
Dealbreakers No cost share required Audit: not stated Reimbursement-only: not stated
Award range
Up to $500,000
Expected awards
Not specified
Application deadline
Jul 5, 2029
Posted
Jun 16, 2026
Last verified
5 days ago

At a glance

No plain-language summary yet for this grant — the official description below is the best source.

What it funds

  • Health
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

This Notice of Funding Opportunity (NOFO) will support, through the cooperative agreement mechanism, investigator-initiated observational studies or biomarker validation studies that require prospective collection of data/biospecimens or continued analysis of data/biospecimens.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.121 · Oral Diseases and Disorders Research

Real awards this federal program has made — the whole assistance listing (93.121), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 155 $429,000 $306,500 – $571,863
FY 2025 277 $429,000 $310,295 – $829,259
FY 2024 301 $491,193 $310,985 – $1,283,003
FY 2023 320 $444,000 $298,673 – $1,756,575
FY 2022 295 — —
FY 2021 305 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,653 — award counts are complete.

Who wins it Higher education (1,224), Nonprofit (242), Business (71) of 1,653 awards — categories can overlap.
Top states CA (124) · PA (83) · MA (82) · NY (70) · TX (35)
Largest recent awards
  1. TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $6,128,166 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $4,961,133 · FY 2023
  3. RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK $4,002,156 · FY 2023
  4. DANA-FARBER CANCER INSTITUTE, INC. $3,742,682 · FY 2025
  5. TRUSTEES OF INDIANA UNIVERSITY $3,736,064 · FY 2023

Source: USASpending.gov · refreshed Aug 16, 2026