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Simpler Grants

No. PAR-27-064 · National Institutes of Health

Open

NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)

Dealbreakers No cost share required Audit: not stated Reimbursement-only: not stated
Award range
Not specified
Expected awards
Not specified
Application deadline
Jul 5, 2029
Posted
Jun 16, 2026
Last verified
5 days ago

At a glance

No plain-language summary yet for this grant — the official description below is the best source.

What it funds

  • Health
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

This notice of funding opportunity (NOFO) encourages applications for implementation of investigator-initiated, milestone driven clinical trials that need enhanced oversight, and as applicable, include mechanistic studies. Mechanistic work in clinical trials may be of great value because it promotes the understanding of human diseases and the development of future therapeutic modalities. Support is available for clinical trials up to 5 years, as well as for extended clinical trials of 6- or 7-years.Investigators are encouraged to visit this NIH website for additional information about the overall mission and research areas of NIAID.Only one clinical trial may be proposed in each NIAID Clinical Trial Implementation Cooperative Agreement (U01) application. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.855 · Allergy and Infectious Diseases Research

Real awards this federal program has made — the whole assistance listing (93.855), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 1,817 $295,722 $146,402 – $737,210
FY 2025 1,596
FY 2024 1,720
FY 2023 1,711
FY 2022 1,576
FY 2021 1,857

Dollar figures are based on the 1,000 most recent awards we store, not all 10,277 — award counts are complete.

Who wins it Higher education (7,336), Nonprofit (1,735), Business (694) of 10,277 awards — categories can overlap.
Top states CA (122) · MA (85) · NY (78) · PA (69) · TX (47)
Largest recent awards
  1. SCRIPPS RESEARCH INSTITUTE $3,679,976 · FY 2026
  2. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $3,499,366 · FY 2026
  3. UNIVERSITY OF WASHINGTON $3,414,775 · FY 2026
  4. UNIVERSITY OF FLORIDA $3,389,992 · FY 2026
  5. ALBERT EINSTEIN COLLEGE OF MEDICINE $3,204,071 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026