No. RFA-OD-27-003 · National Institutes of Health
INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)
- Award range
- Up to $200,000
- Expected awards
- ~5
- Application deadline
- Jun 15, 2028
- Posted
- May 12, 2026
- Last verified
- 6 days ago
At a glance
No plain-language summary yet for this grant — the official description below is the best source.
What it funds
Official description from grants.gov
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
Who can apply
- City or township governments
- County governments
- For-profit organizations other than small businesses
- Independent school districts
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Others
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities / Indian housing authorities
- Small businesses
- Special district governments
- State governments
Program history
USASpending.govAssistance listing 93.121 · Oral Diseases and Disorders Research
Real awards this federal program has made — the whole assistance listing (93.121), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 155 | $429,000 | $306,500 – $571,863 |
| FY 2025 | 277 | $429,000 | $310,295 – $829,259 |
| FY 2024 | 301 | $491,193 | $310,985 – $1,283,003 |
| FY 2023 | 320 | $444,000 | $298,673 – $1,756,575 |
| FY 2022 | 295 | — | — |
| FY 2021 | 305 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 1,653 — award counts are complete.
- TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $6,128,166 · FY 2023
- THE GENERAL HOSPITAL CORPORATION $4,961,133 · FY 2023
- RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK $4,002,156 · FY 2023
- DANA-FARBER CANCER INSTITUTE, INC. $3,742,682 · FY 2025
- TRUSTEES OF INDIANA UNIVERSITY $3,736,064 · FY 2023
Source: USASpending.gov · refreshed Aug 16, 2026
Assistance listing 93.173 · Research Related to Deafness and Communication Disorders
Real awards this federal program has made — the whole assistance listing (93.173), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 170 | $416,419 | $134,042 – $648,731 |
| FY 2025 | 238 | $418,797 | $187,647 – $1,008,401 |
| FY 2024 | 283 | $464,268 | $152,978 – $1,268,772 |
| FY 2023 | 260 | $689,002 | $272,758 – $1,868,608 |
| FY 2022 | 286 | $570,000 | $145,264 – $2,113,099 |
| FY 2021 | 246 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 1,483 — award counts are complete.
- REGENTS OF THE UNIVERSITY OF MINNESOTA $4,621,171 · FY 2022
- UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES $4,589,310 · FY 2023
- THE JOHNS HOPKINS UNIVERSITY $4,474,844 · FY 2022
- OREGON HEALTH & SCIENCE UNIVERSITY $3,863,432 · FY 2022
- THE LELAND STANFORD JUNIOR UNIVERSITY $3,579,023 · FY 2022
Source: USASpending.gov · refreshed Aug 16, 2026
Assistance listing 93.233 · National Center on Sleep Disorders Research
Real awards this federal program has made — the whole assistance listing (93.233), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 22, 2026
Assistance listing 93.310 · Trans-NIH Research Support
Real awards this federal program has made — the whole assistance listing (93.310), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 115 | $582,838 | $418,649 – $860,735 |
| FY 2025 | 401 | $786,876 | $385,000 – $1,467,198 |
| FY 2024 | 455 | $1,174,898 | $558,715 – $2,057,532 |
| FY 2023 | 643 | $1,437,358 | $1,200,000 – $2,578,153 |
| FY 2022 | 666 | — | — |
| FY 2021 | 689 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 2,969 — award counts are complete.
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $34,424,926 · FY 2023
- THE GENERAL HOSPITAL CORPORATION $33,014,143 · FY 2023
- MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION) $17,574,818 · FY 2024
- TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $16,308,508 · FY 2025
- UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $14,064,599 · FY 2025
Source: USASpending.gov · refreshed Aug 18, 2026
Assistance listing 93.351 · Research Infrastructure Programs
Real awards this federal program has made — the whole assistance listing (93.351), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 139 | $607,409 | $418,448 – $813,252 |
| FY 2025 | 168 | $596,737 | $349,073 – $1,388,571 |
| FY 2024 | 188 | $571,633 | $349,563 – $966,019 |
| FY 2023 | 197 | $590,126 | $340,122 – $1,345,699 |
| FY 2022 | 223 | $571,482 | $334,100 – $755,338 |
| FY 2021 | 163 | $589,686 | $399,709 – $999,500 |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 1,078 — award counts are complete.
- OREGON HEALTH & SCIENCE UNIVERSITY $16,992,533 · FY 2022
- UNIVERSITY OF MISSOURI SYSTEM $6,307,489 · FY 2023
- BAYLOR COLLEGE OF MEDICINE $5,213,369 · FY 2021
- UNIVERSITY OF CALIFORNIA, DAVIS $4,023,900 · FY 2023
- UNIVERSITY OF CALIFORNIA IRVINE $3,694,446 · FY 2025
Source: USASpending.gov · refreshed Aug 30, 2026
Assistance listing 93.395 · Cancer Treatment Research
Real awards this federal program has made — the whole assistance listing (93.395), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 316 | $565,152 | $413,691 – $664,926 |
| FY 2025 | 435 | $677,787 | $402,400 – $1,233,798 |
| FY 2024 | 488 | $1,140,586 | $408,966 – $1,897,871 |
| FY 2023 | 522 | — | — |
| FY 2022 | 519 | — | — |
| FY 2021 | 517 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 2,797 — award counts are complete.
- THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER $6,902,371 · FY 2024
- VIRGINIA COMMONWEALTH UNIVERSITY $5,325,147 · FY 2024
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY $4,597,865 · FY 2024
- PRIVO TECHNOLOGIES, INC. $4,499,992 · FY 2024
- FRED HUTCHINSON CANCER CENTER $4,234,248 · FY 2025
Source: USASpending.gov · refreshed Aug 18, 2026
Assistance listing 93.837 · Cardiovascular Diseases Research
Real awards this federal program has made — the whole assistance listing (93.837), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 910 | $406,108 | $121,423 – $769,962 |
| FY 2025 | 1,358 | $638,002 | $257,444 – $1,262,955 |
| FY 2024 | 1,513 | — | — |
| FY 2023 | 1,478 | — | — |
| FY 2022 | 1,536 | — | — |
| FY 2021 | 1,389 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 8,184 — award counts are complete.
- CHILDRENS HOSPITAL MEDICAL CENTER $6,452,040 · FY 2026
- KAISER FOUNDATION HOSPITALS $3,918,561 · FY 2025
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $3,605,083 · FY 2026
- UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION $3,229,552 · FY 2026
- NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. $3,002,716 · FY 2026
Source: USASpending.gov · refreshed Aug 22, 2026
Assistance listing 93.838 · Lung Diseases Research
Real awards this federal program has made — the whole assistance listing (93.838), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.839 · Blood Diseases and Resources Research
Real awards this federal program has made — the whole assistance listing (93.839), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.840 · Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
Real awards this federal program has made — the whole assistance listing (93.840), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 0 | — | — |
| FY 2025 | 0 | — | — |
| FY 2024 | 1 | $1,998,060 | $1,998,060 – $1,998,060 |
| FY 2023 | 8 | $718,015 | $520,326 – $1,181,909 |
| FY 2022 | 0 | — | — |
| FY 2021 | 0 | — | — |
For comparison, this notice advertises Up to $200,000.
- MICHIGAN PUBLIC HEALTH INSTITUTE $1,332,220 · FY 2023
- INDIANA DEPARTMENT OF HEALTH $1,304,518 · FY 2023
- MINNESOTA DEPARTMENT OF HEALTH $1,141,039 · FY 2023
- SOUTHERN NEVADA HEALTH DIST $762,811 · FY 2023
- COUNTY OF CHARLESTON $673,219 · FY 2023
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.846 · Arthritis, Musculoskeletal and Skin Diseases Research
Real awards this federal program has made — the whole assistance listing (93.846), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 148 | $377,506 | $124,696 – $576,799 |
| FY 2025 | 274 | $432,326 | $224,620 – $1,053,137 |
| FY 2024 | 357 | $473,099 | $306,518 – $1,364,153 |
| FY 2023 | 400 | $611,188 | $300,000 – $1,870,687 |
| FY 2022 | 420 | — | — |
| FY 2021 | 357 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 1,956 — award counts are complete.
- WAKE FOREST UNIVERSITY $10,449,074 · FY 2023
- THE GENERAL HOSPITAL CORPORATION $5,795,791 · FY 2023
- REGENTS OF THE UNIVERSITY OF MICHIGAN $3,579,362 · FY 2023
- VANDERBILT UNIVERSITY MEDICAL CENTER $3,213,591 · FY 2026
- UNIVERSITY OF ALABAMA AT BIRMINGHAM $3,106,910 · FY 2023
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.855 · Allergy and Infectious Diseases Research
Real awards this federal program has made — the whole assistance listing (93.855), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 1,817 | $295,722 | $146,402 – $737,210 |
| FY 2025 | 1,596 | — | — |
| FY 2024 | 1,720 | — | — |
| FY 2023 | 1,711 | — | — |
| FY 2022 | 1,576 | — | — |
| FY 2021 | 1,857 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 10,277 — award counts are complete.
- SCRIPPS RESEARCH INSTITUTE $3,679,976 · FY 2026
- REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $3,499,366 · FY 2026
- UNIVERSITY OF WASHINGTON $3,414,775 · FY 2026
- UNIVERSITY OF FLORIDA $3,389,992 · FY 2026
- ALBERT EINSTEIN COLLEGE OF MEDICINE $3,204,071 · FY 2026
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.865 · Child Health and Human Development Extramural Research
Real awards this federal program has made — the whole assistance listing (93.865), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 386 | $392,826 | $79,188 – $593,582 |
| FY 2025 | 665 | $452,972 | $178,000 – $1,225,547 |
| FY 2024 | 785 | — | — |
| FY 2023 | 835 | — | — |
| FY 2022 | 799 | — | — |
| FY 2021 | 764 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 4,234 — award counts are complete.
- PRESIDENT AND FELLOWS OF HARVARD COLLEGE $16,115,056 · FY 2025
- UNIVERSITY OF MIAMI $15,385,183 · FY 2025
- UNIVERSITY OF WASHINGTON $6,635,347 · FY 2025
- GEORGE WASHINGTON UNIVERSITY (THE) $5,117,920 · FY 2025
- RESEARCH TRIANGLE INSTITUTE $4,847,747 · FY 2025
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.866 · Aging Research
Real awards this federal program has made — the whole assistance listing (93.866), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 795 | $493,972 | $248,999 – $713,195 |
| FY 2025 | 1,033 | $643,089 | $467,538 – $1,733,010 |
| FY 2024 | 1,560 | — | — |
| FY 2023 | 1,539 | — | — |
| FY 2022 | 1,715 | — | — |
| FY 2021 | 1,595 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 8,237 — award counts are complete.
- REGENTS OF THE UNIVERSITY OF MICHIGAN $15,345,206 · FY 2026
- UNIVERSITY OF UTAH $10,793,501 · FY 2025
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $10,223,348 · FY 2026
- SUTTER BAY HOSPITALS $9,466,491 · FY 2025
- TUFTS MEDICAL CENTER PARENT, INC. $8,296,115 · FY 2026
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.867 · Vision Research
Real awards this federal program has made — the whole assistance listing (93.867), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 189 | $440,263 | $132,837 – $633,742 |
| FY 2025 | 309 | $464,903 | $260,661 – $1,026,742 |
| FY 2024 | 408 | $630,967 | $342,920 – $1,431,708 |
| FY 2023 | 401 | $771,099 | $422,359 – $1,867,311 |
| FY 2022 | 391 | — | — |
| FY 2021 | 394 | — | — |
For comparison, this notice advertises Up to $200,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 2,092 — award counts are complete.
- UNIVERSITY OF CALIFORNIA, SAN DIEGO $8,283,963 · FY 2024
- REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $5,256,090 · FY 2023
- OHIO STATE UNIVERSITY, THE $4,539,043 · FY 2025
- ALLEN INSTITUTE $4,260,011 · FY 2025
- THE GENERAL HOSPITAL CORPORATION $4,026,010 · FY 2024
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.879 · Medical Library Assistance
Real awards this federal program has made — the whole assistance listing (93.879), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 31 | $349,875 | $149,897 – $642,658 |
| FY 2025 | 34 | $614,550 | $462,000 – $823,053 |
| FY 2024 | 56 | $485,250 | $224,711 – $995,406 |
| FY 2023 | 53 | $727,873 | $286,324 – $1,435,500 |
| FY 2022 | 61 | $812,919 | $413,880 – $1,390,150 |
| FY 2021 | 63 | $1,329,473 | $351,797 – $1,651,842 |
For comparison, this notice advertises Up to $200,000.
- UNIVERSITY OF UTAH $11,107,283 · FY 2021
- UNIVERSITY OF MARYLAND, BALTIMORE $10,600,468 · FY 2021
- UNIVERSITY OF WASHINGTON $6,868,908 · FY 2021
- THE MEDICAL UNIVERSITY OF SOUTH CAROLINA $6,810,297 · FY 2021
- THE UNIVERSITY OF IOWA $6,236,524 · FY 2021
Source: USASpending.gov · refreshed Aug 24, 2026