No. RFA-OD-27-005 · National Institutes of Health
INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)
- Award range
- Not specified
- Expected awards
- ~4
- Application deadline
- Jun 15, 2028
- Posted
- May 13, 2026
- Last verified
- 3 days ago
At a glance
No plain-language summary yet for this grant — the official description below is the best source.
What it funds
Official description from grants.gov
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) encourages Exploratory/Developmental Phased Innovation (R61/R33) grant applications to support development of clinical trials to treat critical and co-occurring health conditions in individuals with Down syndrome. The proposed research aims should be milestone-driven. The total project period for an application submitted in response to this NOFO may not exceed five years. This NOFO provides support for up to two years (R61 phase) for preliminary/developmental/planning studies, followed by possible transition to clinical trial support (R33) of up to three years, although the total duration of the award may not exceed five years. This NOFO requires measurable R61 milestones.
Who can apply
- City or township governments
- County governments
- For-profit organizations other than small businesses
- Independent school districts
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Others
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities / Indian housing authorities
- Small businesses
- Special district governments
- State governments
Program history
USASpending.govAssistance listing 93.173 · Research Related to Deafness and Communication Disorders
Real awards this federal program has made — the whole assistance listing (93.173), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 170 | $416,419 | $134,042 – $648,731 |
| FY 2025 | 238 | $418,797 | $187,647 – $1,008,401 |
| FY 2024 | 283 | $464,268 | $152,978 – $1,268,772 |
| FY 2023 | 260 | $689,002 | $272,758 – $1,868,608 |
| FY 2022 | 286 | $570,000 | $145,264 – $2,113,099 |
| FY 2021 | 246 | — | — |
Dollar figures are based on the 1,000 most recent awards we store, not all 1,483 — award counts are complete.
- REGENTS OF THE UNIVERSITY OF MINNESOTA $4,621,171 · FY 2022
- UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES $4,589,310 · FY 2023
- THE JOHNS HOPKINS UNIVERSITY $4,474,844 · FY 2022
- OREGON HEALTH & SCIENCE UNIVERSITY $3,863,432 · FY 2022
- THE LELAND STANFORD JUNIOR UNIVERSITY $3,579,023 · FY 2022
Source: USASpending.gov · refreshed Aug 16, 2026
Assistance listing 93.233 · National Center on Sleep Disorders Research
Real awards this federal program has made — the whole assistance listing (93.233), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 22, 2026
Assistance listing 93.310 · Trans-NIH Research Support
Real awards this federal program has made — the whole assistance listing (93.310), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 115 | $582,838 | $418,649 – $860,735 |
| FY 2025 | 401 | $786,876 | $385,000 – $1,467,198 |
| FY 2024 | 455 | $1,174,898 | $558,715 – $2,057,532 |
| FY 2023 | 643 | $1,437,358 | $1,200,000 – $2,578,153 |
| FY 2022 | 666 | — | — |
| FY 2021 | 689 | — | — |
Dollar figures are based on the 1,000 most recent awards we store, not all 2,969 — award counts are complete.
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $34,424,926 · FY 2023
- THE GENERAL HOSPITAL CORPORATION $33,014,143 · FY 2023
- MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION) $17,574,818 · FY 2024
- TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $16,308,508 · FY 2025
- UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $14,064,599 · FY 2025
Source: USASpending.gov · refreshed Aug 18, 2026
Assistance listing 93.350 · National Center for Advancing Translational Sciences
Real awards this federal program has made — the whole assistance listing (93.350), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 106 | $427,386 | $166,500 – $755,137 |
| FY 2025 | 110 | $427,602 | $178,000 – $1,833,042 |
| FY 2024 | 137 | $463,150 | $176,720 – $2,139,478 |
| FY 2023 | 131 | $363,189 | $155,500 – $3,024,000 |
| FY 2022 | 106 | $438,741 | $156,117 – $1,906,971 |
| FY 2021 | 76 | $324,197 | $28,713 – $1,276,814 |
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $46,369,962 · FY 2022
- TRUSTEES OF TUFTS COLLEGE $44,451,810 · FY 2023
- PRESIDENT AND FELLOWS OF HARVARD COLLEGE $43,319,327 · FY 2023
- REGENTS OF THE UNIVERSITY OF MICHIGAN $39,816,036 · FY 2023
- THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER $39,349,638 · FY 2021
Source: USASpending.gov · refreshed Aug 30, 2026
Assistance listing 93.395 · Cancer Treatment Research
Real awards this federal program has made — the whole assistance listing (93.395), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 316 | $565,152 | $413,691 – $664,926 |
| FY 2025 | 435 | $677,787 | $402,400 – $1,233,798 |
| FY 2024 | 488 | $1,140,586 | $408,966 – $1,897,871 |
| FY 2023 | 522 | — | — |
| FY 2022 | 519 | — | — |
| FY 2021 | 517 | — | — |
Dollar figures are based on the 1,000 most recent awards we store, not all 2,797 — award counts are complete.
- THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER $6,902,371 · FY 2024
- VIRGINIA COMMONWEALTH UNIVERSITY $5,325,147 · FY 2024
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY $4,597,865 · FY 2024
- PRIVO TECHNOLOGIES, INC. $4,499,992 · FY 2024
- FRED HUTCHINSON CANCER CENTER $4,234,248 · FY 2025
Source: USASpending.gov · refreshed Aug 18, 2026
Assistance listing 93.837 · Cardiovascular Diseases Research
Real awards this federal program has made — the whole assistance listing (93.837), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 910 | $406,108 | $121,423 – $769,962 |
| FY 2025 | 1,358 | $638,002 | $257,444 – $1,262,955 |
| FY 2024 | 1,513 | — | — |
| FY 2023 | 1,478 | — | — |
| FY 2022 | 1,536 | — | — |
| FY 2021 | 1,389 | — | — |
Dollar figures are based on the 1,000 most recent awards we store, not all 8,184 — award counts are complete.
- CHILDRENS HOSPITAL MEDICAL CENTER $6,452,040 · FY 2026
- KAISER FOUNDATION HOSPITALS $3,918,561 · FY 2025
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $3,605,083 · FY 2026
- UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION $3,229,552 · FY 2026
- NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. $3,002,716 · FY 2026
Source: USASpending.gov · refreshed Aug 22, 2026
Assistance listing 93.838 · Lung Diseases Research
Real awards this federal program has made — the whole assistance listing (93.838), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.839 · Blood Diseases and Resources Research
Real awards this federal program has made — the whole assistance listing (93.839), not just this notice.
No grants-family awards recorded for this program since FY 2021 — it may be new, renamed, or not yet reported to USASpending.
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.840 · Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
Real awards this federal program has made — the whole assistance listing (93.840), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 0 | — | — |
| FY 2025 | 0 | — | — |
| FY 2024 | 1 | $1,998,060 | $1,998,060 – $1,998,060 |
| FY 2023 | 8 | $718,015 | $520,326 – $1,181,909 |
| FY 2022 | 0 | — | — |
| FY 2021 | 0 | — | — |
- MICHIGAN PUBLIC HEALTH INSTITUTE $1,332,220 · FY 2023
- INDIANA DEPARTMENT OF HEALTH $1,304,518 · FY 2023
- MINNESOTA DEPARTMENT OF HEALTH $1,141,039 · FY 2023
- SOUTHERN NEVADA HEALTH DIST $762,811 · FY 2023
- COUNTY OF CHARLESTON $673,219 · FY 2023
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.846 · Arthritis, Musculoskeletal and Skin Diseases Research
Real awards this federal program has made — the whole assistance listing (93.846), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 148 | $377,506 | $124,696 – $576,799 |
| FY 2025 | 274 | $432,326 | $224,620 – $1,053,137 |
| FY 2024 | 357 | $473,099 | $306,518 – $1,364,153 |
| FY 2023 | 400 | $611,188 | $300,000 – $1,870,687 |
| FY 2022 | 420 | — | — |
| FY 2021 | 357 | — | — |
Dollar figures are based on the 1,000 most recent awards we store, not all 1,956 — award counts are complete.
- WAKE FOREST UNIVERSITY $10,449,074 · FY 2023
- THE GENERAL HOSPITAL CORPORATION $5,795,791 · FY 2023
- REGENTS OF THE UNIVERSITY OF MICHIGAN $3,579,362 · FY 2023
- VANDERBILT UNIVERSITY MEDICAL CENTER $3,213,591 · FY 2026
- UNIVERSITY OF ALABAMA AT BIRMINGHAM $3,106,910 · FY 2023
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.847 · Diabetes, Digestive, and Kidney Diseases Extramural Research
Real awards this federal program has made — the whole assistance listing (93.847), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 616 | $537,141 | $153,319 – $771,172 |
| FY 2025 | 659 | $730,832 | $270,038 – $1,572,806 |
| FY 2024 | 929 | — | — |
| FY 2023 | 961 | — | — |
| FY 2022 | 975 | — | — |
| FY 2021 | 1,012 | — | — |
Dollar figures are based on the 1,000 most recent awards we store, not all 5,152 — award counts are complete.
- BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE $6,282,406 · FY 2026
- THE LELAND STANFORD JUNIOR UNIVERSITY $5,583,712 · FY 2026
- RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA $5,180,852 · FY 2026
- NORTHWESTERN UNIVERSITY $4,764,127 · FY 2025
- UNIVERSITY OF SOUTH FLORIDA $4,640,761 · FY 2026
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.865 · Child Health and Human Development Extramural Research
Real awards this federal program has made — the whole assistance listing (93.865), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 386 | $392,826 | $79,188 – $593,582 |
| FY 2025 | 665 | $452,972 | $178,000 – $1,225,547 |
| FY 2024 | 785 | — | — |
| FY 2023 | 835 | — | — |
| FY 2022 | 799 | — | — |
| FY 2021 | 764 | — | — |
Dollar figures are based on the 1,000 most recent awards we store, not all 4,234 — award counts are complete.
- PRESIDENT AND FELLOWS OF HARVARD COLLEGE $16,115,056 · FY 2025
- UNIVERSITY OF MIAMI $15,385,183 · FY 2025
- UNIVERSITY OF WASHINGTON $6,635,347 · FY 2025
- GEORGE WASHINGTON UNIVERSITY (THE) $5,117,920 · FY 2025
- RESEARCH TRIANGLE INSTITUTE $4,847,747 · FY 2025
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.866 · Aging Research
Real awards this federal program has made — the whole assistance listing (93.866), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 795 | $493,972 | $248,999 – $713,195 |
| FY 2025 | 1,033 | $643,089 | $467,538 – $1,733,010 |
| FY 2024 | 1,560 | — | — |
| FY 2023 | 1,539 | — | — |
| FY 2022 | 1,715 | — | — |
| FY 2021 | 1,595 | — | — |
Dollar figures are based on the 1,000 most recent awards we store, not all 8,237 — award counts are complete.
- REGENTS OF THE UNIVERSITY OF MICHIGAN $15,345,206 · FY 2026
- UNIVERSITY OF UTAH $10,793,501 · FY 2025
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $10,223,348 · FY 2026
- SUTTER BAY HOSPITALS $9,466,491 · FY 2025
- TUFTS MEDICAL CENTER PARENT, INC. $8,296,115 · FY 2026
Source: USASpending.gov · refreshed Aug 23, 2026