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Simpler Grants

No. PAR-25-445 · National Institutes of Health

Open

NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)

grants.gov listing Full announcement (NOFO)
Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement
Award range
Not specified
Expected awards
Not specified
Application deadline
Oct 3, 2026
Posted
Sep 15, 2025
Last verified
3 days ago

At a glance

AI summary

This program funds Clinical Research Center grants for research in hearing, balance, smell, taste, voice, speech, or language. Applications must be multidisciplinary and include 3 to 4 integrated research projects around one unifying theme, plus one required administrative core and an external advisory committee; 1 to 2 scientific cores are optional. Eligible applicants include a wide range of U.S. institutions and organizations, including nonprofits, universities, governments, tribes, and businesses, but foreign organizations and non-U.S. components of U.S. organizations are not eligible to apply. Clinical trials are optional, but if included they must be low-risk or basic science experimental studies involving humans; applications with higher-risk trials are not responsive. New applications are limited to $1.5 million per year in direct costs, renewals may request up to the lesser of 10% above the last year’s budget or $2 million, the project period may be up to 5 years, and no cost sharing is required.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Research & Discovery
  • Patients & People with Health Conditions
  • Biomedical & Disease Research
Official description from grants.gov

The National Institute on Deafness and Other Communication Disorders (NIDCD) invites applications for Clinical Research Center Grants designed to advance the diagnosis, prevention, treatment, and amelioration of human sensory and communication disorders. For this announcement, Clinical Research is defined as research involving individuals with a sensory and/or communication disorder, or data/tissues from individuals with a sensory and/or communication disorder. Examples of such research include but are not limited to, studies of the prevention, pathogenesis, pathophysiology, diagnosis, treatment, management or epidemiology of a disease or disorder of hearing, balance, smell, taste, voice, speech, or language. Although the intent is that all the research will involve individuals with sensory and/or communication disorders or data/tissues from individuals with sensory and/or communication disorders, when the clinical research goal(s) warrant(s) limited departures from this intent, alternatives (e.g., non-human research, human subjects without a sensory or communication disorder, human at risk for a sensory and/or communication disorder) are possible with appropriate and strong scientific justification and in consultation with NIDCD staff. Applications may propose a low-risk clinical trial but are not required to (optional).Non-responsive applications will not be reviewed. Prospective applicants are strongly encouraged to read this funding opportunity carefully and communicate with the scientific/research contact listed at the end of this award as early as possible to discuss their application plans.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.173 · Research Related to Deafness and Communication Disorders

Real awards this federal program has made — the whole assistance listing (93.173), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 170 $416,419 $134,042 – $648,731
FY 2025 238 $418,797 $187,647 – $1,008,401
FY 2024 283 $464,268 $152,978 – $1,268,772
FY 2023 260 $689,002 $272,758 – $1,868,608
FY 2022 286 $570,000 $145,264 – $2,113,099
FY 2021 246 — —

Dollar figures are based on the 1,000 most recent awards we store, not all 1,483 — award counts are complete.

Who wins it Higher education (1,127), Nonprofit (192), Business (83) of 1,483 awards — categories can overlap.
Top states MA (107) · CA (101) · NY (89) · PA (78) · MD (30)
Largest recent awards
  1. REGENTS OF THE UNIVERSITY OF MINNESOTA $4,621,171 · FY 2022
  2. UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES $4,589,310 · FY 2023
  3. THE JOHNS HOPKINS UNIVERSITY $4,474,844 · FY 2022
  4. OREGON HEALTH & SCIENCE UNIVERSITY $3,863,432 · FY 2022
  5. THE LELAND STANFORD JUNIOR UNIVERSITY $3,579,023 · FY 2022

Source: USASpending.gov · refreshed Aug 16, 2026