No. PAR-27-072 · National Institutes of Health
Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)
- Award range
- Up to $500,000
- Expected awards
- ~50
- Application deadline
- Jul 5, 2029
- Posted
- May 4, 2026
- Last verified
- 8 days ago
At a glance
No plain-language summary yet for this grant — the official description below is the best source.
What it funds
Official description from grants.gov
This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support conventional clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials in any area of research are not sought by and will not be supported through this NOFO. This NOFO does not support commercial production.
Who can apply
- City or township governments
- County governments
- For-profit organizations other than small businesses
- Independent school districts
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Others
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities / Indian housing authorities
- Small businesses
- Special district governments
- State governments
Program history
USASpending.govAssistance listing 93.393 · Cancer Cause and Prevention Research
Real awards this federal program has made — the whole assistance listing (93.393), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 167 | $596,996 | $422,899 – $685,984 |
| FY 2025 | 233 | $743,438 | $397,772 – $1,287,560 |
| FY 2024 | 331 | $1,232,605 | $403,858 – $1,928,145 |
| FY 2023 | 333 | $1,580,141 | $399,888 – $2,324,497 |
| FY 2022 | 371 | — | — |
| FY 2021 | 317 | — | — |
For comparison, this notice advertises Up to $500,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 1,752 — award counts are complete.
- HEALTH RESEARCH, INC. $8,975,418 · FY 2023
- REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $7,529,016 · FY 2024
- WAKE FOREST UNIVERSITY HEALTH SCIENCES $7,411,948 · FY 2023
- VANDERBILT UNIVERSITY MEDICAL CENTER $7,120,874 · FY 2023
- REGENTS OF THE UNIVERSITY OF MINNESOTA $6,827,635 · FY 2023
Source: USASpending.gov · refreshed Aug 14, 2026
Assistance listing 93.394 · Cancer Detection and Diagnosis Research
Real awards this federal program has made — the whole assistance listing (93.394), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 137 | $595,012 | $414,585 – $662,610 |
| FY 2025 | 184 | $726,875 | $399,923 – $1,297,708 |
| FY 2024 | 215 | $1,129,641 | $414,953 – $1,862,878 |
| FY 2023 | 268 | $1,754,736 | $438,924 – $2,398,100 |
| FY 2022 | 277 | $2,036,627 | $596,368 – $3,077,027 |
| FY 2021 | 269 | — | — |
For comparison, this notice advertises Up to $500,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 1,350 — award counts are complete.
- TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $8,347,015 · FY 2022
- BATTELLE MEMORIAL INSTITUTE $6,630,183 · FY 2022
- THE JOHNS HOPKINS UNIVERSITY $6,618,085 · FY 2022
- SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH $6,181,895 · FY 2022
- OREGON HEALTH & SCIENCE UNIVERSITY $5,771,926 · FY 2022
Source: USASpending.gov · refreshed Aug 14, 2026
Assistance listing 93.395 · Cancer Treatment Research
Real awards this federal program has made — the whole assistance listing (93.395), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 316 | $565,152 | $413,691 – $664,926 |
| FY 2025 | 435 | $677,787 | $402,400 – $1,233,798 |
| FY 2024 | 488 | $1,140,586 | $408,966 – $1,897,871 |
| FY 2023 | 522 | — | — |
| FY 2022 | 519 | — | — |
| FY 2021 | 517 | — | — |
For comparison, this notice advertises Up to $500,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 2,797 — award counts are complete.
- THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER $6,902,371 · FY 2024
- VIRGINIA COMMONWEALTH UNIVERSITY $5,325,147 · FY 2024
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY $4,597,865 · FY 2024
- PRIVO TECHNOLOGIES, INC. $4,499,992 · FY 2024
- FRED HUTCHINSON CANCER CENTER $4,234,248 · FY 2025
Source: USASpending.gov · refreshed Aug 18, 2026
Assistance listing 93.396 · Cancer Biology Research
Real awards this federal program has made — the whole assistance listing (93.396), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 289 | $565,909 | $400,614 – $660,808 |
| FY 2025 | 261 | $975,084 | $432,098 – $1,309,674 |
| FY 2024 | 333 | $1,287,771 | $456,103 – $1,958,901 |
| FY 2023 | 383 | $1,541,433 | $747,000 – $2,025,032 |
| FY 2022 | 401 | — | — |
| FY 2021 | 396 | — | — |
For comparison, this notice advertises Up to $500,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 2,063 — award counts are complete.
- RUTGERS, THE STATE UNIVERSITY $11,640,000 · FY 2024
- TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $7,902,036 · FY 2023
- SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE $6,972,263 · FY 2024
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $5,522,226 · FY 2024
- WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY $5,035,979 · FY 2024
Source: USASpending.gov · refreshed Aug 22, 2026
Assistance listing 93.399 · Cancer Control
Real awards this federal program has made — the whole assistance listing (93.399), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 0 | — | — |
| FY 2025 | 1 | $2,490,206 | $2,490,206 – $2,490,206 |
| FY 2024 | 13 | $3,165,783 | $804,361 – $3,227,950 |
| FY 2023 | 7 | $1,121,797 | $947,583 – $1,353,065 |
| FY 2022 | 14 | $4,573,965 | $2,523,875 – $6,154,995 |
| FY 2021 | 5 | $3,186,801 | $2,957,140 – $3,199,301 |
For comparison, this notice advertises Up to $500,000.
- UNIVERSITY OF DELAWARE $16,730,455 · FY 2021
- VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY $8,183,001 · FY 2022
- FRED HUTCHINSON CANCER CENTER $7,696,898 · FY 2022
- THE INSTITUTE FOR CANCER RESEARCH $6,471,989 · FY 2022
- WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY $4,655,326 · FY 2022
Source: USASpending.gov · refreshed Aug 22, 2026
Assistance listing 93.865 · Child Health and Human Development Extramural Research
Real awards this federal program has made — the whole assistance listing (93.865), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 386 | $392,826 | $79,188 – $593,582 |
| FY 2025 | 665 | $452,972 | $178,000 – $1,225,547 |
| FY 2024 | 785 | — | — |
| FY 2023 | 835 | — | — |
| FY 2022 | 799 | — | — |
| FY 2021 | 764 | — | — |
For comparison, this notice advertises Up to $500,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 4,234 — award counts are complete.
- PRESIDENT AND FELLOWS OF HARVARD COLLEGE $16,115,056 · FY 2025
- UNIVERSITY OF MIAMI $15,385,183 · FY 2025
- UNIVERSITY OF WASHINGTON $6,635,347 · FY 2025
- GEORGE WASHINGTON UNIVERSITY (THE) $5,117,920 · FY 2025
- RESEARCH TRIANGLE INSTITUTE $4,847,747 · FY 2025
Source: USASpending.gov · refreshed Aug 23, 2026
Assistance listing 93.867 · Vision Research
Real awards this federal program has made — the whole assistance listing (93.867), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 189 | $440,263 | $132,837 – $633,742 |
| FY 2025 | 309 | $464,903 | $260,661 – $1,026,742 |
| FY 2024 | 408 | $630,967 | $342,920 – $1,431,708 |
| FY 2023 | 401 | $771,099 | $422,359 – $1,867,311 |
| FY 2022 | 391 | — | — |
| FY 2021 | 394 | — | — |
For comparison, this notice advertises Up to $500,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 2,092 — award counts are complete.
- UNIVERSITY OF CALIFORNIA, SAN DIEGO $8,283,963 · FY 2024
- REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $5,256,090 · FY 2023
- OHIO STATE UNIVERSITY, THE $4,539,043 · FY 2025
- ALLEN INSTITUTE $4,260,011 · FY 2025
- THE GENERAL HOSPITAL CORPORATION $4,026,010 · FY 2024
Source: USASpending.gov · refreshed Aug 23, 2026