No. RFA-RM-27-011 · National Institutes of Health
Development and Testing of a Multi-use Frameworks Playbook for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U01 Clinical Trial Not Allowed)
- Award range
- Up to $300,000
- Expected awards
- ~5
- Application deadline
- Oct 9, 2026
- Posted
- Jun 30, 2026
- Last verified
- 2 days ago
At a glance
No plain-language summary yet for this grant — the official description below is the best source.
What it funds
Official description from grants.gov
The overarching goal of this notice of funding opportunity (NOFO) and its companion opportunities is to establish the Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program to support development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools. PRIMED-AI CDS tools are based on the integration of clinical imaging with other types of multimodal health data to enhance care for patients with a wide range of health conditions. The PRIMED-AI Program seeks to catalyze the adoption of AI-based CDS tools into clinical workflows to enable novel personalized medicine strategies that address significant health challenges. The purpose of this NOFO is to solicit applications for the design, development, and preliminary validation of robust frameworks for the application of multimodal-artificial intelligence (AI) models for clinical use. Frameworks developed through these awards would populate a "playbook", defined as a collection of actionable guidelines, standardized protocols, and/or standard operating procedures (SOPs) for reliable and effective development and deployment of multimodal AI tools. It is expected that the frameworks delineated in this playbook will directly address PRIMED-AI objectives and needs, while also remaining flexible enough to enable sufficient extensibility and interoperability for use across a broad spectrum of multimodal biomedical AI applications, both internal and external to the PRIMED-AI Program.
Who can apply
- City or township governments
- County governments
- For-profit organizations other than small businesses
- Independent school districts
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Others
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities / Indian housing authorities
- Small businesses
- Special district governments
- State governments
Program history
USASpending.govAssistance listing 93.310 · Trans-NIH Research Support
Real awards this federal program has made — the whole assistance listing (93.310), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 115 | $582,838 | $418,649 – $860,735 |
| FY 2025 | 401 | $786,876 | $385,000 – $1,467,198 |
| FY 2024 | 455 | $1,174,898 | $558,715 – $2,057,532 |
| FY 2023 | 643 | $1,437,358 | $1,200,000 – $2,578,153 |
| FY 2022 | 666 | — | — |
| FY 2021 | 689 | — | — |
For comparison, this notice advertises Up to $300,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 2,969 — award counts are complete.
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $34,424,926 · FY 2023
- THE GENERAL HOSPITAL CORPORATION $33,014,143 · FY 2023
- MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION) $17,574,818 · FY 2024
- TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $16,308,508 · FY 2025
- UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $14,064,599 · FY 2025
Source: USASpending.gov · refreshed Aug 18, 2026
Change history
Since we first indexed it- Jul 19, 2026 Eligibility text updated
- Jul 19, 2026 Award ceiling set: $300,000
- Jul 11, 2026 Title updated
- Jul 11, 2026 Status: forecasted → open
- Jul 11, 2026 Deadline set: Oct 9, 2026