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Simpler Grants

No. RFA-RM-27-013 · National Institutes of Health

Open

Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional)

Dealbreakers No cost share required Audit: not stated Reimbursement-only: not stated
Award range
Not specified
Expected awards
~8
Application deadline
Oct 19, 2026
Posted
Jun 30, 2026
Last verified
2 days ago

At a glance

No plain-language summary yet for this grant — the official description below is the best source.

What it funds

  • Health
  • Research & Discovery
  • Patients & People with Health Conditions
  • Researchers & Scholars
  • AI, Computing & Cybersecurity
  • Biomedical & Disease Research
Official description from grants.gov

The overarching goal of this notice of funding opportunity (NOFO) and its companion opportunities is to establish the Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program to support development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools. PRIMED-AI CDS tools are based on the integration of clinical imaging with other types of multimodal health data to enhance care for patients with a wide range of health conditions. The PRIMED-AI Program seeks to catalyze the adoption of AI-based CDS tools into clinical workflows to enable novel personalized medicine strategies that address significant health challenges.The purpose of this NOFO is to catalyze the translation of Artificial Intelligence (AI)-enabled, image-centered, multimodal CDS tools, developed as Software as a Medical Device, from training and testing of prototypes towards clinical applications that address unmet health challenges in precision medicine. These projects are expected to have high potential for demonstrable, positive impact on patient outcomes and/or healthcare processes.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide

Program history

USASpending.gov

Assistance listing 93.310 · Trans-NIH Research Support

Real awards this federal program has made — the whole assistance listing (93.310), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 115 $582,838 $418,649 – $860,735
FY 2025 401 $786,876 $385,000 – $1,467,198
FY 2024 455 $1,174,898 $558,715 – $2,057,532
FY 2023 643 $1,437,358 $1,200,000 – $2,578,153
FY 2022 666
FY 2021 689

Dollar figures are based on the 1,000 most recent awards we store, not all 2,969 — award counts are complete.

Who wins it Higher education (2,212), Nonprofit (582), Business (34) of 2,969 awards — categories can overlap.
Top states CA (153) · MA (103) · NY (93) · PA (63) · MI (21)
Largest recent awards
  1. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $34,424,926 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $33,014,143 · FY 2023
  3. MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION) $17,574,818 · FY 2024
  4. TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $16,308,508 · FY 2025
  5. UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $14,064,599 · FY 2025

Source: USASpending.gov · refreshed Aug 18, 2026

Change history

Since we first indexed it
  1. Jul 19, 2026 Eligibility text updated
  2. Jul 11, 2026 Title updated
  3. Jul 11, 2026 Status: forecasted → open
  4. Jul 11, 2026 Deadline set: Oct 19, 2026