No. RFA-RM-27-014 · National Institutes of Health
Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)
- Award range
- Up to $2,000,000
- Expected awards
- ~1
- Application deadline
- Oct 2, 2026 30 days left
- Posted
- Jun 30, 2026
- Last verified
- 2 days ago
At a glance
No plain-language summary yet for this grant — the official description below is the best source.
What it funds
Official description from grants.gov
The overarching goal of this notice of funding opportunity (NOFO) and its companion opportunities is to establish the Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program to support development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools. PRIMED-AI CDS tools are based on the integration of clinical imaging with other types of multimodal health data to enhance care for patients with a wide range of health conditions. The PRIMED-AI Program seeks to catalyze the adoption of AI-based CDS tools into clinical workflows to enable novel personalized medicine strategies that address significant health challenges. The purpose of this NOFO is to solicit applications for the creation of a Validation Center to serve as a dedicated hub for the comprehensive evaluation and characterization of AI-enabled, image-based, multimodal CDS tools developed by the PRIMED-AI Consortium, to ensure these tools are reliable, reproducible, and generalizable. The Validation Center will focus on verification, validation, interoperability, and uncertainty quantification to comprehensively characterize performance of the CDS tools developed by the program. The core functions of the Validation Center will involve the systematic validation of PRIMED-AI Consortium deliverables, including those emerging from award recipients under the Playbook, Data-to-Model Academic-Industrial Partnerships, and Model-to-Clinic NOFOs.
Who can apply
- City or township governments
- County governments
- For-profit organizations other than small businesses
- Independent school districts
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Others
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities / Indian housing authorities
- Small businesses
- Special district governments
- State governments
Program history
USASpending.govAssistance listing 93.310 · Trans-NIH Research Support
Real awards this federal program has made — the whole assistance listing (93.310), not just this notice.
| Fiscal year | Awards | Median award | Middle half |
|---|---|---|---|
| FY 2026 (so far) | 115 | $582,838 | $418,649 – $860,735 |
| FY 2025 | 401 | $786,876 | $385,000 – $1,467,198 |
| FY 2024 | 455 | $1,174,898 | $558,715 – $2,057,532 |
| FY 2023 | 643 | $1,437,358 | $1,200,000 – $2,578,153 |
| FY 2022 | 666 | — | — |
| FY 2021 | 689 | — | — |
For comparison, this notice advertises Up to $2,000,000.
Dollar figures are based on the 1,000 most recent awards we store, not all 2,969 — award counts are complete.
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $34,424,926 · FY 2023
- THE GENERAL HOSPITAL CORPORATION $33,014,143 · FY 2023
- MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION) $17,574,818 · FY 2024
- TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $16,308,508 · FY 2025
- UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $14,064,599 · FY 2025
Source: USASpending.gov · refreshed Aug 18, 2026
Change history
Since we first indexed it- Jul 19, 2026 Eligibility text updated
- Jul 19, 2026 Award ceiling set: $2,000,000
- Jul 11, 2026 Title updated
- Jul 11, 2026 Status: forecasted → open
- Jul 11, 2026 Deadline set: Oct 2, 2026